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Kluyvera ascorbata Bacteremia and Meningitis: A Case Report and Review of the Literature

Walsh, Thomas MD*; Burkitt, Michael MD*; Welc, Christina DO; Verdream, Edward MD‡§∥

Infectious Diseases in Clinical Practice: July 2011 - Volume 19 - Issue 4 - p 247-251
doi: 10.1097/IPC.0b013e31820fc855
Review Articles

Kluyvera is a small, motile, gram-negative bacillus within the Enterobacteriaceae family. It is part of the normal human flora of the respiratory tract and gastrointestinal tract. Although it was originally described as a benign colonizer and saprophyte, Kluyvera has also been described as causing a wide array of serious and potentially life-threatening infections and should not be discounted when isolated from clinical specimens. We report the case of a patient who developed Kluyvera ascorbata bacteremia and probable meningitis. It is the 17th reported case of Kluyvera bacteremia in the literature and would represent the first case of Kluyvera meningitis in a patient without a central nervous system shunt. We review the literature about reported cases of Kluyvera bacteremia and meningitis.

From the *Department of Medicine, The Western Pennsylvania Hospital, Pittsburgh, PA; †Division of Infectious Disease, Virginia Commonwealth University, Richmond, VA; ‡Division of Infectious Disease, The Western Pennsylvania Hospital; §Division of Infectious Disease, Allegheny General Hospital; and ∥Division of Infectious Disease, The Western Pennsylvania Hospital Forbes Regional Campus, Pittsburgh, PA.

Correspondence to: Thomas Walsh, MD, Department of Medicine, The Western Pennsylvania Hospital, 4800 Friendship Ave, Pittsburgh, PA 15224. E-mail:

No organizations with a financial interest invested in this article including NIH, Wellcome Trust, and Howard Hughes Medical Institute (HHMI).

The authors have no conflicts of interest to disclose.

© 2011 Lippincott Williams & Wilkins, Inc.