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Mucormycosis as a Pathogen in Polymicrobial Necrotizing Fasciitis

Dinasarapu, Chandrasekhar R. MD*; Auerbach, Jena DO; Levi, Michael H. ScD; Corpuz, Marilou MD§

Infectious Diseases in Clinical Practice: November 2010 - Volume 18 - Issue 6 - p 417-418
doi: 10.1097/IPC.0b013e3181e85dfb
Case Reports

Mucormycosis is rare, and its incidence is difficult to calculate accurately. The causative agents are saprophytic fungi of the class Zygomyces, order Mucorales. Rhinocerebral disease, the most common form, which accounts for more than half of the cases, is associated with diabetes and ketoacidosis. The syndromes of pulmonary and disseminated mucormycosis are usually seen in neutropenic patients. The development of primary cutaneous infection from mucormycosis depends on underlying systemic illness and local host factors. Although mucormycosis is infrequent, more cases of cutaneous infections are being noted, especially in the compromised host. We describe a case of Mucor as a predominant organism in a polymicrobial soft tissue infection in a diabetic patient with necrotizing fasciitis.

From the Departments of *Medicine, †Pathology, ‡Diagnostic Microbiology and §Infectious Diseases, Montefiore Medical Center, Bronx, NY.

Correspondence to: Chandrasekhar R. Dinasarapu, MD, MPH, Department of Medicine, 5th Floor, Montefiore Medical Center (North Division), 600 East 233rd St, Bronx, NY 10466. E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2010 Lippincott Williams & Wilkins, Inc.