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Austrian Syndrome (Triad of Pneumococcal Pneumonia, Meningitis and Endocarditis) in an Intravenous Drug User: A Case Report

Nog, Rajat MD*; Zaheer, Naima MD; Badshah, Cyrus MD, PhD*

Infectious Diseases in Clinical Practice: November 2010 - Volume 18 - Issue 6 - p 406-407
doi: 10.1097/IPC.0b013e3181db807f
Case Reports

The clinical triad of pneumococcal pneumonia, meningitis, and endocarditis known as Austrian syndrome is associated with a high mortality rate despite appropriate antibiotic usage, unless surgically managed when indicated. The most common risk factor for Austrian syndrome is alcoholism. We present a case of Austrian syndrome in an intravenous drug user (IVDU) where none of the previously described risk factors for the syndrome were present. There has been only 1 other report of Austrian syndrome in an IVDU. A high index of suspicion for this syndrome may be warranted in IVDUs who also present with both pneumococcal pneumonia and meningitis. Echocardiography early in the disease course may identify concurrent endocarditis and indications for surgical intervention with resultant decrease in mortality associated with the syndrome.

From the *Division of Infectious Diseases, Department of Medicine Columbia University, College of Physicians and Surgeons, The affiliation at Harlem Hospital, New York, NY; and †Infectious Disease Consultant, Las Vegas, NV.

Correspondence to: Rajat Nog, MD, Division of Infectious Diseases, Department of Medicine, Harlem Hospital Center, MLK Pavilion, Room 3-101, 506 Lenox Ave, New York, NY 10037; E-mail:

The authors have no funding or conflicts of interest to disclose.

© 2010 Lippincott Williams & Wilkins, Inc.