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Disseminated Bipolaris Infection

Choudhry, Asad MS II*; Tucci, Veronica MD; Greene, John N. MD, FACP‡§

Infectious Diseases in Clinical Practice: September 2010 - Volume 18 - Issue 5 - p 296-298
doi: 10.1097/IPC.0b013e3181d5e127
Review Articles

Bipolaris is an opportunistic pathogen widely distributed in air, soil, and plants. It is increasingly being recognized as the cause of fungal sinusitis in both normal and immunocompromised hosts. We report a case of disseminated infection due to Bipolaris in a 43-year-old man with prolonged neutropenia after chemotherapy for leukemia. A high-resolution computed tomography (CT) scan of the chest revealed a linear opacity in the right lower lobe, small right pleural effusion, and multiple low-density masses within the liver. A bronchoalveolar lavage was performed, and cultures taken subsequently yielded the fungal pathogen, Bipolaris. The patient was successfully treated with liposomal amphotericin B and posaconazole.

From the *Services Institute of Medical Sciences, Lahore, Pakistan; †Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, University of South Florida College of Medicine; ‡Infectious Diseases and Hospital Epidemiology, Moffitt Cancer Center and Research Institute, Internal Medicine & Oncological Science; and §University of South Florida College of Medicine, Tampa, FL.

Correspondence to: John N. Greene, MD, FACP, Moffitt Cancer Center and Research Institute, 12902 Magnolia Dr, FOB-3, Tampa, FL 33612-9497. E-mail:

The authors report no conflicts of interest.

© 2010 Lippincott Williams & Wilkins, Inc.