Severe renal adverse effects have been documented after intravenous immune globulin (IVIG) therapy. This is the first reported case of successfully using IVIG to treat a patient with Clostridium difficile infection with concomitant acute renal failure where the patient did not experience a worsening of renal function. The use of IVIG in C. difficile and the mechanism of renal failure secondary to IVIG are reviewed. In addition, a brief overview of IVIG use in patients with acute renal failure is included.
From the Division of Pharmacy Practice, St Louis College of Pharmacy, St Louis, MO.
Reprints: Jennifer S. Hardesty, PharmD, Pharmacy Practice, St Louis College of Pharmacy, 4588 Parkview Pl, St Louis, MO, 63110. E-mail: firstname.lastname@example.org.
The authors have no funding or conflicts of interest to disclose.
This material has not been previously presented and is not being submitted concurrently elsewhere.