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Community-Acquired Legionnaires Disease in Croatia: Clinical and Radiographic Evaluation

Viskovic, Klaudija MD, PhD*; Puljiz, Ivan MD, PhD; Dakovic Rode, Oktavija MD, MSc; Klasnic, Ksenija BSc§; Kujundzic Tiljak, Mirjana MD, PhD; Kuzman, Ilija MD, PhD

Infectious Diseases in Clinical Practice: January 2010 - Volume 18 - Issue 1 - p 23-28
doi: 10.1097/IPC.0b013e3181b7f809
Original Articles

Legionella pneumophila is a well-recognized etiologic factor in community-acquired pneumonia (CAP). We analyzed the course of radiographic findings of 49 patients with Legionnaires disease, correlated them with clinical and laboratory parameters, and compared them with CAP caused by Mycoplasma pneumoniae, Chlamydophila pneumoniae, and Coxiella burnetii. The most common radiographic finding at admission was unilobar, patchy infiltrate localized in the lower lobes. At follow-up radiography 4 to 12 days after admission, 42.9% of patients developed progression of infiltrates. Mean complete clearing of the infiltrates in most patients (83.7%) was noted on the 21st day of the onset of symptoms. Most patients with Legionnaires disease presented with a clinically mild-to-moderate form, and radiographic findings differed from those seen in other atypical CAPs.

From the Departments of *Radiology, †General Infectious Diseases, and ‡Microbiology, University Hospital for Infectious Diseases; Departments of §Sociology, Faculty of Humanities and Social Sciences, and ∥Medical Statistics, Epidemiology and Medical Informatics, "Andrija Štampar" School of Public Health, School of Medicine, University of Zagreb; and ¶Department of Respiratory Infections, University Hospital for Infectious Diseases and School of Medicine, University of Zagreb, Zagreb, Croatia.

Reprints: Klaudija Viskovic, MD, PhD, University Hospital for Infectious Diseases, Mirogojska cesta 8, 10000 Zagreb, Croatia. E-mail:;

The authors have no funding or conflicts of interest to disclose.

© 2010 Lippincott Williams & Wilkins, Inc.