A 49-year-old veterinarian presented with a primary bacteremia of Streptococcus equi subsp. zooepidmicus, pancytopenia, and splenomegaly. Hairy cell leukemia (HCL) was diagnosed and successfully treated with cladribine. Group C streptococci are animal pathogens and rarely cause infections in humans. Comorbidity is often essential for acquiring a severe group C streptococci infection. Granulocytopenia and impaired T cell immunity make hairy cell leukemia patients susceptible for severe infections.
From the Departments of Internal Medicine, *Máxima Medical Centre, Veldhoven; †Jeroen Bosch Hospital, Den Bosch; and ‡Department of MedicalMicrobiology, Máxima Medical Centre, Veldhoven, The Netherlands.
Reprints: Jaap ten Oever, MD, Máxima Medical Centre, Department of Internal Medicine, PO Box 7777, 5500 MB Veldhoven, The Netherlands. E-mail: firstname.lastname@example.org.