Epidural abscess with bone involvement is a rare manifestation of central nervous system cryptococcal infection. Both immunocompromised and immunocompetent patients can present with a painless swelling of the head that may or may not be accompanied with headache. Definitive diagnosis requires stain and culture of tissue. The overall prognosis is good when adequate surgical drainage and extended antifungal therapy are administered; however, the optimal duration of treatment is not determined at this time.
From the Department of Infectious Diseases, Saint Louis University Hospital, St Louis, MO.
Reprints: Musab U. Saeed, MD, Department of Infectious Diseases, 3635 Vista at Grand (FDT-8N), St Louis, MO 63110-0250. E-mail: firstname.lastname@example.org.