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Rhabdomyolysis as the Presenting Manifestation of Acute Human Immunodeficiency Virus Infection in an Adolescent: Case Report and Literature Review

Maniar, Alok J. MB, BS*; Tolan, Robert W. Jr MD†‡

Infectious Diseases in Clinical Practice: January 2009 - Volume 17 - Issue 1 - p 12-16
doi: 10.1097/IPC.0b013e318184d767
Review Articles

Rhabdomyolysis is the degeneration of skeletal muscle due to several causes, which are broadly classified as traumatic and nontraumatic. Although rhabdomyolysis is a recognized complication of long-term human immunodeficiency virus (HIV) infection, and as a possible toxicity of many antiretroviral medications, it is extraordinarily rare as a presenting manifestation of acute HIV seroconversion illness. We report an adolescent with HIV seroconversion in whom rhabdomyolysis was the presenting manifestation.

From the *HIV Clinical Trials Unit, Division of Infectious Diseases, Thomas Jefferson University Hospital, Philadelphia, PA; †Division of Allergy, Immunology and Infectious Diseases, The Children's Hospital at Saint Peter's University Hospital, New Brunswick, NJ; and ‡Drexel University College of Medicine, Philadelphia, PA.

Reprints: Robert W. Tolan, Jr, MD, MOB 3110, 254 Easton Ave, New Brunswick, NJ 08901. E-mail:

The authors received no financial support for the preparation of this report and have no conflicts of interest to report.

© 2009 Lippincott Williams & Wilkins, Inc.