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Panton-Valentine Leukocidin-Positive Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia Presenting as Fever of Unknown Origin

Gonzalez, Blanca E. MD*; Williams, Suzanne CPNP-AC*; Rios, Yanet MD; Faverio, Luis MD; Churchill, Robin B. MD*

Infectious Diseases in Clinical Practice: January 2009 - Volume 17 - Issue 1 - p 55-57
doi: 10.1097/IPC.0b013e3181758e69
Case Reports

Panton-Valentine leukocidin-producing strains of Staphylococcus aureus have been linked to rapidly progressive severe necrotizing pneumonia with low survival rates. We describe a previously healthy child who presented in a nontoxic fashion with prolonged fever and a radiographic picture of pulmonary nodules caused by a Panton-Valentine leukocidin-producing S. aureus. Complete resolution was achieved after 4 weeks of antimicrobial therapy.

From the *Division of Pediatric Infectious Diseases, †Pediatric Hospitalist Service, and ‡Pediatric Pulmonary Service, The Children's Hospital of Southwest Florida, Fort Myers, FL.

Reprints: Blanca E. Gonzalez, MD, The Children's Hospital of Southwest Florida, 16261 Bass Rd, Suite 100, Fort Myers, FL 33919. E-mail:

© 2009 Lippincott Williams & Wilkins, Inc.