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Histologic Comparison of Light Emitting Diode Phototherapy-Treated Hydroxyapatite-Grafted Extraction Sockets: A Same-Mouth Case Study

Brawn, Peter R. DDS*; Kwong-Hing, Alan DDS, MSc

doi: 10.1097/ID.0b013e318065a84c
Basic and Clinical Research

Background: The stimulating effect of red and near-infrared (NIR) laser phototherapy on bone regeneration and growth has been shown in a number of in vitro and animal studies. However, the effect of NIR phototherapy on the bone regeneration of hydroxyapatite (HA) -treated extraction sockets has not been previously demonstrated.

Materials and Methods: An investigational Biolux extraoral light emitting diode phototherapy device was used daily for 21 days postextraction and socket grafting with HA (Osteograf LD300) unilaterally. Bone regeneration of the phototherapy-treated and nontreated side wascompared in same-mouth extraction sockets.

Results: Histologic evaluations showed enhanced bone formation and faster particle resorption associated with the phototherapy-treated socket graft compared with the non-phototherapy-treated socket.

Conclusions: The accelerated bone healing in the phototherapy-treated HA socket graft may provide faster implant placement compared to nonorphototherapy-treated socket grafts.

*Private Practice, Nanaimo, British Columbia, Canada.

†Adjunct Professor, Division of Periodontics, Schulich School of Medicine and Dentistry, University of Western Ontario and Private Practice of Dentistry, Toronto, Ontario, Canada.

Reprint requests and correspondence to:

Peter Brawn, DDS; 343 Railway St, Suite 203; Vancouver, BC V6A 1A4, Canada; Phone: (250) 740–0027; Fax: (604) 357-1115; E-mail:

© 2007 Lippincott Williams & Wilkins, Inc.