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Basic and Clinical Research

Bone Microstrain Values of 1-Piece and 2-Piece Implants Subjected to Mechanical Loading

Harel, Noga DMD*; Eshkol-Yogev, Inbar DMD*; Piek, Dana DMD*; Livne, Shiri DMD*; Lavi, David DMD*; Ormianer, Zeev DMD

Author Information
doi: 10.1097/ID.0b013e3182926199
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Abstract

Frost1 postulated that there is a regulatory mechanism that adapts bone mass according to the intensity of microstrains (μ[Latin Small Letter Open E]) generated inside the osseous tissue at the bone-implant interface. For example, 200 μ[Latin Small Letter Open E] is less associated with bone atrophy from under stimulation, 200 to 2500 μ[Latin Small Letter Open E] is equated with balanced bone remodeling (steady state), 2500 to 4000 μ[Latin Small Letter Open E] may trigger bone growth (hypertrophy), and 4000 μ[Latin Small Letter Open E] or greater can theoretically lead to bone resorption (eg, pathological overload).1 Natural teeth and dental implants distribute forces differently in the surrounding bone.2 The main biomechanical difference is that dental implants lack a stress-reducing element, such as the periodontal ligament, which exists around natural teeth to absorb and distribute occlusal forces to the supporting bone.3 In addition, natural teeth contain mechanoreceptors that sense the mechanical load and provide important feedback to the patient regarding potential dangers to the dentition when chewing hard substances.4,5 From a biomechanical perspective, the physiological and anatomical differences between natural teeth and implants greatly impact force distribution and microstrains within the supporting bone.6–10

Dental implants must fulfill certain criteria: biocompatibility, adequate mechanical strength, optimum soft and hard tissue integration, and transmission of functional forces to bone within physiological limits.11,12 One of the critical elements influencing the long-term uncompromised functioning of a dental implant is its design.13–15 Implant design is characterized by its composition material, overall shape, thread design, prosthetic platform, abutment connection, surface topography, and physiochemical composition, all of which determine its biomechanical behavior.16–20

The implant-abutment connection affects stress distribution in bone.21,22 Baggi et al23 investigated the influence of implant diameter and length on stress distribution to calculate the overload risk in crestal bone around the implant neck. They found that stress values and concentration areas decreased in cortical bone when implant diameter increased; whereas more effective stress distributions for cancellous bone were experienced with increasing implant length.

Stress distribution in bone may also be affected by different abutment connections, such as internal and external designs.18,24–26 Differences in stress distribution patterns between implants with external or internal hex connections were compared using in vitro models.23 External hex implants showed an increase in microstrains at the cervical area under horizontal load, whereas in internal hex implants, microstrains were located in the implant's apical region.22 These findings suggested that internal hex implant designs widely distributed forces down to their apical regions compared with the crestal bone concentrations of external hex implants.

In contrast to 2-piece (2P) implant designs, 1-piece (1P) implant systems consist of the implant and abutment manufactured together from a single section of titanium bar stock. This completely eliminates the implant-abutment connection. An FEA study was conducted to investigate the effect of 3 different abutment types on the stress distribution in bone when subjected to inclined loads.26 The study found that 1P implants transferred loads evenly throughout the implant system and into the bone. However, the maximum Von Mises stress generated in bone with the 1P implant was always higher than the stresses generated with the 2P internal hex implant, regardless of load angle inclination. In the case of the 2P internal hex implant, the tapered frictional joint connection between the abutment and the implant neck reduced the effect of bending caused by the horizontal component of inclined load.

Another FEA study19 analyzed the force transmission and distribution characteristics of 1P and 2P implants and found that 2P implants experienced higher mechanical stress under oblique loading. Other FEA studies found similar force distribution patterns in different implant designs.27,28 Several variables can adversely affect the predictive accuracy of FEA models, such as model geometry, material properties, applied boundary conditions, and the bone-implant interface.29 Because these variables may be different in each study, FEA results may be inconsistent from one study to the next. Other techniques for analyzing microstrains in peri-implant bone include the use of strain gauges, photoelastic models, or a combination of these methods. In contrast to the FEA method, strain gauge results are measured clinically rather than digitally. Strain gauges are also generally bonded directly to, or in, the vicinity of the implant surface,30,31 and the implants are generally embedded in a photoelastic model rather than in bone. However, no studies, to date, have bonded strain gauges to the bone surface for the comparison of 1P and 2P implants.16,17,32,33

This article reports on a study that was conducted to compare the microstrains generated in peri-implant bone by 1P and 2P implant systems.

Materials and Methods

Osteotomies were sequentially prepared in a bovine rib using a reduction contra-angle (Nouvag AG, Goldach, Switzerland) and sequential cutting with internally irrigated drills. A 1P implant (Zimmer One-Piece Implant; Zimmer Dental, Inc., Carlsbad, CA) and 2P implant (Tapered Screw-Vent; Zimmer Dental, Inc.) were placed into the osteotomies according to the manufacturer's protocols. A screw-retained abutment (Hex-Lock Contour Abutment; Zimmer Dental, Inc.) was attached to the 2P implant and tightened to 20 Ncm with a calibrated torque wrench.

The distance from the implant apexes to bone cortex was about 2 mm in both samples (Fig. 1). Two linear strain gauges, 350 Ω nominal distance, were placed around each implant on the bone surface 1 mm from the cervical part (C2A-13-062LW-350; Vishay Measurements Group, Inc., Holon, Israel) and 1 mm from its apical part (C2A-06-125LW-350; Vishay Measurements Group, Inc.) (Fig. 2). The measurement direction was parallel to the long axis of the implant on the tension side. The strain gauges were covered with AE 10 EPOXY and cemented to the bone (M-BOND 200; Vishay Measurements Group, Inc.). The strain gauges were connected to a strain indicator (Vishay 2100; Vishay Measurement Group, Inc.). Each test specimen was mounted at a 30-degree angle in a mechanical testing machine (Instron 4502; High Wycombe, Buckinghamshire, United Kingdom). Loading at a 30-degree angle was achieved by mounting the implant in angulations and vertical loading (Fig. 3). Each sample was tested in 5 cycles with 4 loading measurements between 20 and 120 N. After every cycle, the test setup with the implant was removed from the machine and released for a few seconds and then reconnected again at the same position.

Fig. 1
Fig. 1:
X-ray of the 1P implant after inserted into the bovine bone. The implant is angulated to create 30 degrees in loading.
Fig. 2
Fig. 2:
The strain gauges connected directly to the bone surface in the apical and cervical parts of the implants.
Fig. 3
Fig. 3:
The Instron loading machine creates vertical pressure on the abutment connected to the implant, resembling nonaxial loading.

Statistical Analysis

Four t tests were performed to assess 2 intergroup and 2 intragroup comparisons:

  • Intergroup comparison of neck values between 1P and 2P implants.
  • Intergroup comparison of apical values between 1P and 2P implants.
  • Intragroup comparison of neck and apical values of the 1P implant.
  • Intragroup comparison of neck and apical values of the 2P implant.

Before t tests were considered, a Folded F test was performed to test the assumption of equal variances. If the Folded F test was statistically significant (P < 0.05), then a Satterthwaite t test was calculated.

Results

The microstrains measured around 1P implants were significantly higher than those measured around 2P implants (Table 1). The higher values were recorded at both the cervical and apical ends of the implants. The average microstrain at the apex was 71.6 µ[Latin Small Letter Open E] in the 1P implant and 17.3 µ[Latin Small Letter Open E] in the 2P implant. At the cervical end, the average microstrain was 132 µ[Latin Small Letter Open E] in the 1P implant and approximately 60 µ[Latin Small Letter Open E] in the 2P implant.

Table 1
Table 1:
Comparison Between 1P and 2P Implants

In both 1P and 2P implants, microstrains measured around the cervical end (“neck”) were significantly higher than those at the apical end (“apex”) (Table 2). In 1P implants, the average microstrain was 71.6 µ[Latin Small Letter Open E] at the apical end and 132 µ[Latin Small Letter Open E] at the neck. In 2P implants, the average microstrain was 17.34 µ[Latin Small Letter Open E] at the apical part and 59.4 µ[Latin Small Letter Open E] at the neck.

Table 2
Table 2:
Comparisons of Strains Around Neck and Apex of Implants

Discussion

In this study, microstrain levels in the peri-implant bone of 1P and 2P implant systems were measured and compared. Abutment type (removable/2P implants or nonremovable/1P implants) significantly influenced stress distributions in bone because of differences in load transfer mechanisms and the size of the implant-abutment contact area. Thus, different implant-abutment configurations may positively or adversely affect stress levels in peri-implant bone, which can trigger different bone remodeling responses.1 In the 1P implants, load was transferred more evenly in both the implant body and surrounding bone than in the 2P implants. In another study, Dittmer et al21 evaluated the abutments from 5 different implant systems and found that the type of implant-abutment connection significantly influenced the load-bearing capacity of implants. In contrast to indirect stress measurements generated in FEA19,23,24,26–28,34 and photoelastic31,35 studies, the present study model measured peri-implant stresses directly on the bone.

In general, microstrains measured in the cervical region of the implant were significantly higher than those measured in the apical region of the implant, regardless of the implant design. When the 2 implant designs were compared, however, cervical and apical microstrains measured around the 1P implants were significantly higher than those measured around the 2P implants. The results correlate with an FEA analysis conducted by Chun et al,26 which found the stress differences between implants with internal and external connections, in the 1P implant designs. The internal hex connection reduced the bending effect by sliding the tapered joints between the implant and the abutment and thus reduced Von Mises stresses.26

Long-term clinical evaluation is needed to assess if the higher microstrains measured around 1P implants in this mechanical study would be capable of inducing higher bone resorption at the clinical level. Of the few short-term prospective studies that have evaluated bone loss around 1P implants, most of the implants were reported to have some marginal bone loss of 1 to 2 mm.36–39 Taking into consideration the fact that 1P implants have no implant-abutment microgap, a question arises as to whether the observed bone loss was attributable to implant design, surgical technique, clinician learning curve,29 or some other factors. An important consideration is the fact that 1P implants are always immediately loaded to some degree regardless of the planned prosthetic scheme. Bone loss may thus be attributable to premature implant loading when the transmucosal post is subjected to lip, tongue, and cheek pressures and inadvertent contact with food boluses during chewing, even when the implant is not intentionally placed into function.

The use of bovine bone to simulate the clinical condition may be more accurate than other studies that use resin (photoelastic models) or computerized models (FEA) to evaluate the stress distribution. A major limitation of this study, however, was the small sample size of implants examined. Prospective clinical research is needed to determine the long-term effects of load distribution around implants and abutments of various designs.

Conclusions

Within the limitations of this study, 1P implants exhibited numerically higher peri-implant microstrains in both the cervical and apical regions than 2P implants in the same length and diameter, but the effect that this difference in magnitude might have on peri-implant bone maintenance could not be evaluated in the present model.

Disclosures

The authors claim to have no financial interest, either directly or indirectly, in the products or information listed in the article.

References

1. Frost HM. Bone "mass" and the "mechanostat": A proposal. Anat Rec. 1987;219:1–9.
2. Skalak R. Biomechanical considerations in osseointegrated prostheses. J Prosthet Dent. 1983;49:843–848.
3. Jacobs R, Bou Serhal C, van Steenberghe D. The stereognostic ability of natural dentitions versus implant-supported fixed prostheses or overdentures. Clin Oral Investig. 1997;1:89–94.
4. Johansson RS, Olsson KA. Microelectrode recordings from human oral mechanoreceptors. Brain Res. 1976;118:307–311.
5. Dong WK, Chudler EH, Martin RF. Physiological properties of intradental mechanoreceptors. Brain Res. 1985;334:389–395.
6. Hekimoglu C, Anil N, Cehreli MC. Analysis of strain around endosseous dental implants opposing natural teeth or implants. J Prosthet Dent. 2004;92:441–446.
7. Pilliar RM, Deporter DA, Watson PA, et al.. Dental implant design—Effect on bone remodeling. J Biomed Mater Res. 1991;25:467–483.
8. Weinberg LA, Kruger B. Biomechanical considerations when combining tooth-supported and implant-supported prostheses. Oral Surg Oral Med Oral Pathol. 1994;78:22–27.
9. Duyck J, Van Oosterwyck H, Vander Sloten J, et al.. Magnitude and distribution of occlusal forces on oral implants supporting fixed prostheses: An in vivo study. Clin Oral Implants Res. 2000;11:465–475.
10. Ishigaki S, Nakano T, Yamada S, et al.. Biomechanical stress in bone surrounding an implant under simulated chewing. Clin Oral Implants Res. 2003;14:97–102.
11. Albrektsson T, Brånemark PI, Hansson HA, et al.. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52:155–170.
12. Brunski JB. Biomaterials and biomechanics in dental implant design. Int J Oral Maxillofac Implants. 1988;3:85–97.
13. Abuhussein H, Pagni G, Rebaudi A, et al.. The effect of thread pattern upon implant osseointegration. Clin Oral Implants Res. 2010;21:129–136.
14. Kohn DH. Overview of factors important in implant design. J Oral Implantol. 1992;18:204–219.
15. Renouard F, Nisand D. Impact of implant length and diameter on survival rates. Clin Oral Implants Res. 2006;17(3 suppl 2):35–51.
16. Siegele D, Soltesz U. Numerical investigations of the influence of implant shape on stress distribution in the jaw bone. Int J Oral Maxillofac Implants. 1989;4:333–340.
17. Chun HJ, Cheong SY, Han JH, et al.. Evaluation of design parameters of osseointegrated dental implants using finite element analysis. J Oral Rehabil. 2002;29:565–574.
18. Binon PP. Implants and components: Entering the new millennium. Int J Oral Maxillofac Implants. 2000;15:76–94.
19. Cehreli MC, Akça K, Iplikçioğlu H. Force transmission of one- and two-piece morse-taper oral implants: A nonlinear finite element analysis. Clin Oral Implants Res. 2004;15:481–489.
20. Van Oosterwyck H, Duyck J, Vander Sloten J, et al.. The influence of bone mechanical properties and implant fixation upon bone loading around oral implants. Clin Oral Implants Res. 1998;9:407–418.
21. Dittmer S, Dittmer MP, Kohorst P, et al.. Effect of implant-abutment connection design on load bearing capacity and failure mode of implants. J Prosthodont. 2011;20:510–516.
22. Maeda Y, Satoh T, Sogo M. In vitro differences of stress concentrations for internal and external hex implant-abutment connections: A short communication. J Oral Rehabil. 2006;33:75–78.
23. Baggi L, Cappelloni I, Di Girolamo M, et al.. The influence of implant diameter and length on stress distribution of osseointegrated implants related to crestal bone geometry: A three-dimensional finite element analysis. J Prosthet Dent. 2008;100:422–431.
24. Akça K, Cehreli MC, Iplikçioglu H. A comparison of three-dimensional finite element stress analysis with in vitro strain gauge measurements on dental implants. Int J Prosthodont. 2002;15:115–121.
25. Rangert B, Jemt T, Jörneus L. Forces and moments on Branemark implants. Int J Oral Maxillofac Implants. 1989;4:241–247.
26. Chun HJ, Shin HS, Han CH, et al.. Influence of implant abutment type on stress distribution in bone under various loading conditions using finite element analysis. Int J Oral Maxillofac Implants. 2006;21:195–202.
27. Nagasawa S, Hayano K, Niino T, et al.. Nonlinear stress analysis of titanium implants by finite element method. Dent Mater J. 2008;27:633–639.
28. Bozkaya D, Muftu S, Muftu A. Evaluation of load transfer characteristics of five different implants in compact bone at different load levels by finite elements analysis. J Prosthet Dent. 2004;92:523–530.
29. Lambert PM, Morris HF, Ochi S. Positive effect of surgical experience with implant on second-stage implant survival. J Oral Maxillofac Surg. 1997;55(12 suppl 5):12–18.
30. Kim WD, Jacobson Z, Nathanson D. In vitro stress analyses of dental implants supporting screw-retained and cement-retained prostheses. Implant Dent. 1999;8:141–151.
31. Akça K, Cehreli MC. A photoelastic and strain-gauge analysis of interface force transmission of internal-cone implants. Int J Periodontics Restorative Dent. 2008;28:391–399.
32. Cehreli MC, Akkocaoglu M, Comert A, et al.. Human ex vivo bone tissue strains around natural teeth vs. immediate oral implants. Clin Oral Implants Res. 2005;16:540–548.
33. Akça K, Akkocaoglu M, Cömert A, et al.. Bone strains around immediately loaded implants supporting mandibular overdentures in human cadavers. Int J Oral Maxillofac Implants. 2007;22:101–109.
34. Geng JP, Tan KB, Liu GR. Application of finite element analysis in implant dentistry: A review of the literature. J Prosthet Dent. 2001;85:585–598.
35. Bernardes SR, de Araujo CA, Neto AJ, et al.. Photoelastic analysis of stress patterns from different implant-abutment interfaces. Int J Oral Maxillofac Implants. 2009;24:781–789.
36. Finne K, Rompen E, Toljanic J. Three-year prospective multicenter study evaluating marginal bone levels and soft tissue health around a one-piece implant system. Int J Oral Maxillofac Implants. 2012;27:458–466.
37. Heijdenrijk K, Raghoebar GM, Meijer HJ, et al.. Feasibility and influence of the microgap of two implants placed in a non-submerged procedure: A five-year follow-up clinical trial. J Periodontol. 2006;77:1051–1060.
38. Finne K, Rompen E, Toljanic J. Clinical evaluation of a prospective multicenter study on 1-piece implants. Part 1: Marginal bone level evaluation after 1 year of follow-up. Int J Oral Maxillofac Implants. 2007;22:226–234.
39. Hahn JA. Clinical and radiographic evaluation of one-piece implants used for immediate function. J Oral Implantol. 2007;33:152–155.
Keywords:

bone; microstrain 1-piece implant

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