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BASIC AND CLINICAL RESEARCH

Treatment of the Contaminated Implant Surface Using the Er,Cr:YSGG Laser

Miller, Robert J. DDS, FACD*

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doi: 10.1097/01.ID.0000127521.06443.0B
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Abstract

With modern oral implantology celebrating the close of its fifth decade, treatment planning using dental implants has become the standard of care. Although the predominant modality is the endosseous root-form implant, a significant number of plate-form and subperiosteal implants continue to be used in appropriate cases. As a result of 2 decades of research involving the tissue–implant interface, using roughened or bioactive surfaces, success rates have risen dramatically. If we accept the published figures for implant success from multicenter studies, we find that success rates now exceed 95%. 1,2

It is estimated that the number of endosseous implants that will be placed this year will surpass a half million. 3 Using the survival tables from previously published studies, we must therefore accept the reality that, even with this high percentage of success, a significant number of implants will develop soft or hard tissue problems and could go from ailing to failure mode if not treated in a timely and effective fashion. Although the body of knowledge for implant placement has increased geometrically, scant resources have been developed for definitively treating the problem implant.

When faced with the ailing implant, one must first understand the etiology of the problem. The first qualification is to determine if the defect is of infective or biomechanical origin. 4 If the implant is occlusally overloaded, the biomechanical parameter must be treated first. If the implant is surgically treated before addressing the occlusal problem, it is highly probable that the defect will not respond to treatment. If the lesion is of infective origin without a biomechanical component, one must determine if the defect is purely a soft tissue problem or if it involves soft and hard tissue components. Ultimately, regardless of the etiology, only definitive treatment of the implant will provide a stable interface for possible long-term survival and function. 5

Implant surfaces have gone through an evolutionary change, from machined titanium to macro-porous geometry. The first endosseous implants had a relatively smooth texture that was created through the machining process. This machined titanium surface (Fig. 1) allowed direct bone apposition while the relative smoothness of this surface helped to prevent bacterial colonization. With good periodontal care, even those implants with saucerization defects were easily maintained by scaling and chemotherapeutic modalities. 6

Fig. 1.
Fig. 1.:
Machined titanium surface.

The second-generation implant surface was a titanium plasma sprayed (TPS) coating (Fig. 2). Research indicated that a roughened surface increased wetability and enhanced bone growth along the surface of the implant resulting in direct apposition of bone to titanium. 7 This surface, although enhancing implant stability in bone, created an environment for increased plaque and bacterial colonization often resulting in osseous and soft tissue dehiscence. Early attempts at treatment consisted of apically repositioning flaps and removing the roughened surface. This could result in poor implant/crown ratios and resultant failure from biomechanical overloading.

Fig. 2.
Fig. 2.:
Titanium plasma spray (TPS) surface.

A third-generation implant surface consisted of blasting the implant body with an abrasive and then acid etching (SLA) to remove the abrasive contaminant. 8 This etching procedure resulted in a more defined ratio of peaks and valleys to increase wetability even further (Fig. 3). However, this increased definition on the implant surface creates a more ideal surface for bacterial colonization and compromises our ability to maintain the implant when the body of the implant is contaminated or exposed.

Fig. 3.
Fig. 3.:
Sand-blasted, acid-etched (SLA) surface.

One current generation of implant surfaces uses a sintering technique (Fig. 4) to create 3-dimensional ingrowth of bone so that shorter implants can be used. 9 However, this surface becomes the most problematic when it becomes infected because normal maintenance procedures will not completely clean the implant surface. Even surgical treatment using chemical means might not completely de-bride the sintered surface.

Fig. 4.
Fig. 4.:
Sintered surface.

Bioactive coatings (HA) have also been used to decrease healing times and increase percentage of bone to implant contact. Although the roughness of these coatings is similar to that of TPS or SLA, an added problem is the dissolution or fracture of the coatings in the presence of inflammation. This could speed up bacterial colonization and bone loss, making timely treatment of these implants that much more important. 10

Previous surgical treatment modalities involved both mechanical debridement (hand scaling, ultrasonics) and chemical surface treatment (tetracycline hydrochloride paste, 40% citric acid ph1, EDTA). 11 These modalities have significant shortcomings. With regard to mechanical treatment of the implant body, alteration of the implant surface could occur. Damage to the surface of the implant could delay or prevent bone regrowth. Incomplete debridement of bacterial colonization and endotoxins could result in failure of grafted sites and a return of the defect. 12 If chemical surface treatment is used, tetracycline paste should be used only on titanium surfaces (CP or titanium alloy). If it is used on HA surfaces, it will interfere with the Ca-P bond of bone and could delay healing. Tetracycline is used to decontaminate the implant but is not effective in removing bacterial endotoxin from the implant surface. 13 The use of citric acid could result in a chemical burn of hard and soft tissue and an organic smear layer, also delaying healing. Citric acid is used to basically freshen the HA surface. 14 It could, however, alter the crystalline surface making it more prone to breakdown after grafting. Ethyl-enediaminetetraacetic acid (EDTA) has been used to remove the organic smear layer on the implant body after treatment to eliminate granulation tissue in the osseous defect. 15

A new paradigm for the treatment of the implant surface has been developed after the introduction of the Erbium, Chromium:Yttrium, Scandium, Gallium, Garnet (Er,Cr: YSGG) laser. 16 Previous lasers tested for potential use in oral implantology include Nd:YAG, Ho: YAG, GaAlAS, CO2, and Er:YAG. 17 Most of these lasers, however, function in vaporization mode. High temperatures could alter or damage the implant surface making them inappropriate for use in treating the implant defect. They could also result in charring or coagulation of tissue, delaying the reparative cascade. The Er,Cr:YSGG laser, operating at 2780 nm, ablates tissue by a hydrokinetic process that prevents temperature rise. The following research protocol evaluated the YSGG laser for potential use in debridement of the contaminated implant surface before osseous grafting.

Materials and Methods

The evaluation of the efficacy of YSGG laser treatment of the implant body consisted of 2 parts. First was a study of the potential effects of the YSGG laser on the titanium surface under available power settings. Current dental implants come in a range of titanium grades, from commercially pure (CP 1–4) to Ti-6Al-4Va alloys. 18 A soft grade (CP-2) implant was chosen because this would be the most easily deformed or damaged as compared with titanium alloy. Second was a study of the ability to remove the hardest material that one could encounter on the implant surface. This material was determined to be an appositional crystalline HA coating. A comparison was also made using the most common protocol for debridement of the implant body (citric acid). The implant system chosen for the study was Interpore IMZ press-fit cylinders (Interpore International, Irvine, CA).

The implants were divided into 2 groups: a TPS group that included a control (Fig. 5), citric acid-washed, and laser-treated implant, and an HA group that contained a control (Fig. 6), citric acid-washed, and laser-treated implant. The implants remained in their sterile containers until the testing began to avoid inadvertent contamination. The control implants remained sealed until the scanning electron microscope (SEM) evaluation. SEM magnification was set at 25× and 2500× at the junction of the polished collar and roughened surface. The Er,Cr:YSGG laser (Biolase Technology, Inc., San Clemente, CA) was used with a 600-μm tip and at a power setting of 6.00 W (maximum power). Additional parameters used were air pressure setting at 100 and water spray at 32. The combination of highest power and relatively low water setting would maximize any potential thermal effects and act as a threshold for comparison of any additional power settings.

Fig. 5.
Fig. 5.:
TPS control implant at 25× and 2500× magnification.
Fig. 6.
Fig. 6.:
HA control implant.

The TPS implant group was evaluated by citric acid wash (40%, ph1) and laser application. The citric acid wash was applied for 3 minutes and was followed by a 1-minute sterile saline rinse (Fig. 7). The laser-treated implant was also treated for 3 minutes followed by a 1-minute sterile saline rinse (Fig. 8). The HA group (Figs. 9 and 10) was treated by the identical protocol. The implants were immediately placed back into their containers and sent to the University of Miami SEM Laboratory for analysis.

Fig. 7.
Fig. 7.:
Citric acid wash of the TPS implant. Note the organic smear layer remaining even after saline rinse.
Fig. 8.
Fig. 8.:
YSGG treatment of the TPS implant at high power (6 W). Note the absence of surface alteration of the polished collar and roughened surface.
Fig. 9.
Fig. 9.:
Citric acid wash of the HA implant. Incomplete debridement of HA and loss of crystallinity.
Fig. 10.
Fig. 10.:
YSGG treatment of a HA implant. Almost complete removal of the appositional HA coating with no alteration of the underlying titanium surface.

Results

The SEM study of the TPS and HA-coated implants revealed the following. The YSGG-treated TPS implant revealed no measurable change in surface morphology at the highest power setting (6 W) and at a relatively low water setting. There was no organic smear layer and the surface remained identical to the control implant. The citric acid-washed TPS implant revealed no measurable change to surface morphology but an organic smear layer remained even after a sterile saline rinse.

The YSGG-treated HA implant revealed almost complete ablation of the appositional HA coating and no measurable change in the underlying roughened surface. There was no organic smear layer. The citric acid-treated HA implant revealed grossly incomplete coating removal, an organic smear layer, and a loss of crystallinity of the remaining bioactive coating.

Discussion

In a comparison of a widely used technique for implant debridement (citric acid) and the new protocol of laser ablation, it is clear that the Er,Cr: YSGG laser is highly efficient and effective in removing contaminants from the implant body. Unlike previous laser systems that operate with a high thermal coefficient, the YSGG laser will not alter the surface characteristics of the roughened titanium surface. The absence of any measurable changes to the titanium surface and the lack of an organic smear layer creates the ideal environment for the regrowth of bone and potential reintegration of the exposed or contaminated area of the implant body. There is no coagulation, charring, or burning of the adjacent tissue. The absence of cell lysis prevents the initiation of an inflammatory process. This allows adjacent bone and soft tissue cells to go directly to a regenerative phase, which significantly shortens the healing process. One must be prepared, after preparation of the implant surface, to graft the osseous defect and to protect the grafted site with a membrane. 19 Like with previous techniques, it might be desirable to take the implant out of function and achieve primary closure to prevent soft tissue invagination and fluid contamination of the graft. If this is not possible, a resorbable membrane should be used to avoid a secondary surgical procedure to remove the membrane after healing.

Conclusion

Generational changes in implant design and surface technology have dramatically increased implant success rates. The bone-to-implant bond has been enhanced and shorter healing times to loading have become the rule rather than the exception. Although implant dentistry has become highly predictable, treatment of the ailing implant still relies on old methodology. This article has presented a potential new paradigm for the treatment of the ailing implant that is periodontally involved. Its application for debridement of the implant body is demonstrably superior to the older mechanical and chemical treatments of the implant surface. The Er,Cr: YSGG laser has the potential for multiple applications in oral implantology, including periimplant osseous and soft tissue recontouring as well as implant maintenance. Using the hydrokinetic properties of this laser system, we could ultimately replace much of the hand instrumentation currently used in our surgical procedures and do so with less trauma, faster healing, and greater patient comfort.

Disclosure

The author claims to have no financial interest in any company or any of the products mentioned in this article.

References

1. Pikos M, Cannizzaro G, Korompilas L, et al. International retrospective multi-center study of 8130 HA-coated cylinder dental implants: 5-year survival data. Int Magazine Oral Implantol. 2002;1:6–15.
2. Jeffcoat M, McGlumphy E, Ready M, et al. A comparison of hydroxyapatite (HA)-coated threaded, HA-coated cylindric, and titanium threaded endosseous dental implants. Int J Oral Maxillofacial Implants. 2002;18:406–410.
3. US Markets for Dental Implants: annual industry report. Implant Dentistry. 2003;12:108–111.
4. El-Askary AS, Meffert RM, Griffin T. Why do implants fail? Part I. Implant Dentistry. 1999;8:173–183.
5. Meffert RM. Treatment of failing dental implants. Curr Opin Dent. 1992;2:109–144.
6. Quinynen M, Listgarten MA. The distribution of bacterial morphotypes around natural teeth and titanium implants ad modum Branemark. Clin Oral Implant Res. 1990;1:8–12.
7. Gatewood RR, Cobb CM, Killoy WJ. Microbial colonization on natural tooth structure compared with smooth and plasma-sprayed implant surfaces. Clin Oral Implants Res. 1993;4:53–64.
8. Buser D, Merickske-Stern R, Dula K, et al. Clinical experience with one-stage, non-submerged dental implants. Advances Dental Res. 1999;13:153–161.
9. Deporter DA, Todescan R Jr, Pilliar RM, et al. Sintered, porous-surfaced dental implants: pushing the envelope of current practice. Int Mag Oral Impl. 2003;4:53–60.
10. El-Askary AS, Meffert RM, Griffin T. Why do implants fail? Part II. Implant Dentistry. 1999;8:265–276.
11. Zablotsky MH, Diedrich DL, Meffert RM. Detoxification of endotoxin-contaminated titanium and hydroxyapatite-coated surfaces utilizing various chemotherapeutic and mechanical modalities. Implant Dentistry. 1992;1:154–158.
12. Zablotsky MH. A retrospective analysis of the management of ailing and failing endosseous dental implants. Implant Dentistry. 1998;7:185–189.
13. Dennison DK, Huerzeler MB, Quinones C, et al. Contaminated implant surfaces: an in vitro comparison of implant surface coating and treatment modalities for decontamination. J Periodontol. 1994;65:942–948.
14. Meffert RM. Maintenance of dental implants. In: Misch CE, ed. Contemporary Implant Dentistry. St. Louis: Mosby Yearbook;1993:735–762.
15. Kornman KS, Robertson PB. Fundamental principles affecting the outcomes of therapy for osseous lesions. Periodontol 2000. 2000;22:22–43.
16. Eversole LR, Rizoiu IM. Preliminary investigations on the utility of an Erbium, Chromium YSGG laser. CDA J. 1995;23:41–47.
17. Kreisler M, Gotz H, Duschner H, et al. Effect of Nd:YAG, Ho:YAG, CO2, and GaAlAs laser irradiation on surface properties of endosseous dental implants. Int J Oral Maxillo Impl. 2002;17:202–211.
18. Lemons JE, Dietsh-Misch F. Bio-materials for dental implants. In: Misch CE, ed. Contemporary Implant Dentistry, 2nd ed. St. Louis: Mosby; 1999:271–302.
19. Rose LF, Rosenberg E. Bone grafts and growth and differentiation factors for regenerative therapy: a review. Prac Proc Aesth Dent. 2001;13:725–734.

Abstract Translations [German, Spanish, Portugese, Japanese]

AUTOR: Robert J. Miller, DDS, FACD*. *Vorsitzender der Abteilung für Oralimplan-tologie in der Atlantic Coast Klinik für zahnmedizinische Forschung, Palm Beach, FL, und privat praktizierender Arzt, Delray Beach, FL. Schriftverkehr: Robert J. Miller, DDS, FACD, Fachzentrum für ästhetische und implantatgestützte Zahnheilkunde (Center für Advanced Aesthetic and Implant Dentistry), 16244 South Military Trail, Suite 260, Delray Beach, FL, 33484. Telefon.: 561-499-5665, Fax: 561-381-7775. eMail: millerbeardog1@aol.com

Behandlung kontaminierter Implantatoberflächen mittels Er,Cr:YSGG-Laser

ZUSAMMENFASSUNG: Die kontaminierte Oberfläche eines Implantats mit mechanischen und chemotherapeutischen Methoden zu behandeln, erwies sich als nur bedingt erfolgreich. Eine unvollständige Wundversorgung der Oberfläche durch Wundtoilette sowie Veränderungen der Implantatoberfläche können eventuelle Behandlungsversuche zur Transplantation und Reintegration des Implantatkörpers erschweren. Es wurde ein Lasersystem mit einer operativen Wellenlänge von 2780 nm entwickelt, die Abtragung basiert auf einem hydrokinetischen Prozess. Damit sind weit verbesserte Möglichkeiten zur Dekontaminierung und Wundtoilette gegeben. Der vorliegende Bericht präsentiert eine Bewertung des Er,Cr:YSGG-Lasers sowie einen Vergleich zu den geläufigsten chemotherapeutischen Behandlungsmethoden bei Behandlung von Implantatoberflächen. Des Weiteren wird eine SEM-Studie vorgestellt, die die Abtragungsmethodik mittels YSGG-Laser mit Zitronensäurebehandlungen von mit TPS und HA beschichteten Im-plantatoberflächen vergleicht. Diese Ergebnisse lassen den Schluss zu, dass die Lasera-btragungsmethode mit YSGG-Laser sehr gut zur Beseitigung eventueller Kontaminierungen auf aufgerauten Implantatoberflächen geeignet ist. Die Titanbasis blieb von der Behandlung unberührt.

SCHLÜSSELWÖRTER: Wundtoilette mittels Laser, hydrokinetisch, YSGG-Laser

AUTOR: Robert J. Miller, DDS, FACD*. *Jefe, Departamento de Implantología Oral en la Clínica de Investigación Dental Costa Atlántica, Palm Beach, FL y práctica privada, Delray Beach, FL. Correspondencia a: Robert J. Miller, DDS, FACD, Center for Advanced Aesthetic and Implant Dentistry, 16244 South Military Trail, Suite 260, Delray Beach, FL 33484-6505. Teléfono: 561-499-5665, Fax: 561-381-7775. Correo electrónico: millerbeardog1@aol.com

Tratamiento de la superficie contaminada del implante usando el láser Er, Cr:YSGG.

ABSTRACTO: El tratamiento de la superficie contaminada del implante a través de métodos mecánicos y quimioterapéuticos ha logrado resultados inconclusos. Un desbridamiento incompleto de la superficie o alteración de la superficie del implante podría comprometer los intentos del injerto y reintegración del cuerpo del implante. El desarrollo de un sistema láser que funcione a 2780nm y usando un proceso ablativo hidrokinético ofrece la posibilidad de una descontaminación y desbridamiento más eficiente. Se evaluó y comparó el láser Er,Cr:YSGG con la modalidad quimioterapéutica usada más comúnmente para el tratamiento de la superficie del implante. Se presenta un estudio de SEM comparando la ablación YSGG con el tratamiento con ácido cítrico de la superficie recubierta del implante TPS y HA. Podemos concluir que la ablación del láser usando el láser YSGG es altamente eficiente en la eliminación de contaminantes potenciales en la superficie áspera del implante mientras que no demuestra efectos sobre el sustrato de titanio.

PALABRAS CLAVES: desbridamiento con láser, hidrokinético, láser YSGG

AUTOR: Robert J. Miller, Doutor em Ciência Dentária, Membro do American College of Dentists. *Chefe do Departamento de Implatologia Oral na Clínica de Pesquisa Dentária Atlantic Coast, Palm Beach, FL, e Clínica Privada, Delray Beach, Fl. Correspondência para: Robert J. Miller, DDS, FACD, Center for Advanced Aesthetic and Implant Dentistry, 16244 South Military Trail, Suite 260, Delray Beach, FL 33484-6505. Telefone: 561-499-5665, Fax: 561-381-7775. E-mail: millerbeardog1@aol.com

Tratamento da Superfície de Implante Contaminada Usando o Laser Er,Cr:YSGG

RESUMO: O tratamento da superfície do implante contaminado por meio mecânico e quimioterapêutico teve sucesso variado. O desbridamento incompleto da superfície ou a alteração da superfície do implante pode comprometer tentativas de transplatne de tecido e reintegração da matéria do implante. O desenvolvimento de um sistema a laser operando em 2780nm e usando um processo ablativo hidrocinético oferece a possibilidade de descontaminação e desbridamento mais eficientes. O laser Er,Cr:YSGG é avaliado e comparado com a modalidade quimioterapêutica mais comumente usado para o tratamento da superfície do implante. É apresentado um estudo SEM comparando a ablação YSGG ao tratamento com ácido cítrico da superfície do implante coberta por TPS e HA. Podemos concluir que a ablação a laser usando o laser YSGG é altamente eficiente na remoção de potenciais contaminantes na superfície de implante tornada áspera, enquanto não demonstra nenhum efeito no substrato de titânio.

PALAVRAS-CHAVE: desbridamento a laser, hidrocinético, laser YSGG

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Keywords:

laser debridement; hydrokinetic; YSGG laser

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