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Immediate Postextractive Implants With and Without Bone Graft

3-year Follow-up Results From a Multicenter Controlled Randomized Trial

Mastrangelo, Filiberto, MD, DDS*; Gastaldi, Giorgio, MD, DDS; Vinci, Raffaele, MD, DDS; Troiano, Giuseppe, DDS; Tettamanti, Lucia, MD, DDS§; Gherlone, Enrico, MD, DSS; Lo Muzio, Lorenzo, MD, DSS

doi: 10.1097/ID.0000000000000816
Basic and Clinical Research
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Purpose: To evaluate the outcome of single postextraction immediate implants placed with and without bone grafts in the esthetic maxillary premolar area for 3-year follow-up after loading.

Material and Methods: After tooth extraction, 102 patients received 115 immediate dental implants. Patients were randomly allocated to immediate implant placement with (group A: 51) or without (group B: 51) anorganic bovine bone and resorbable collagen barrier.

Results: After 3 years (T36), 1 implant failed in each group. Thirty-seven patients showed inflammation and bleeding, 19 mucositis, and 2 periimplantitis. Statistical significant association was found between BOP and mucositis at T12 (P < 0.0005) and T36 (P < 0.0005). The mesial bone level was −0.61 mm in group B and −1.01 mm in group A (P < 0.001). The group B distal bone level was −0.71 mm and −1.12 mm in group A (P < 0.005). Group B's buccal mean probing was increased (+0.40 mm) than group A (+0.36 mm). Group B's palatal mean value was higher (+0.54 mm) than group A (+0.38 mm). No statistically significant differences were found between the 2 groups. However, the Pink Esthetic Score and patient satisfaction were higher in group B than A (P < 0.001).

Conclusions: The use of anorganic bovine bone substitute with a resorbable collagen barrier in immediate postextractive implants seems to improve the esthetic outcomes after a 3-year follow-up.

*Aggregate Professor, PhD Oral Surgery Specialist, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

Associate Professor, Department of Dentistry and Implantology, ISCCR San Raffaele Vita e Salute University, Milan, Italy.

Post-Doc Researcher, Laboratory Coordinator and data analysis, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

§Associate Professor, Department of Oral Science, University of Insubria, Varese, Italy.

Professor and Chairman, Department of Dentistry and Implantology, ISCCR San Raffaele Vita e Salute University, Milan, Italy.

Professor and Chairman, Department of Clinical and Experimental Medicine, University of Foggia, Italy.

Reprint requests and correspondence to: Filiberto Mastrangelo, MD, DDS, PhD, Department of Clinical and Experimental Medicine, University of Foggia, Via L. Rovelli n°50, Foggia 71122, Italy, Phone: +39.335.8390720, Fax: +39.085.44054213, E-mail: filibertomastrangelo@hotmail.com

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