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De Novo Grown Bone on Exposed Implant Surfaces Using Photodynamic Therapy and Recombinant Human Bone Morphogenetic Protein-2: Case Report

Schuckert, Karl-Heinz DMD, MD, PhD*; Jopp, Stefan MD, PhD; Muller, Ulrich DMD, PhD

doi: 10.1097/01.id.0000247856.09740.3f
Clinical Science and Techniques
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The reconstruction of bone on exposed implant surfaces requires an almost complete elimination of attached bacteria. Only then is new bone growth possible. This case report describes a new way to kill biofilms with photodynamic therapy and to augment bone by using recombinant human bone morphogenetic protein-2. Though the newtechnique of bone tissue engineering causes some problems, new bone growth on uncovered implant surfaces is successful to a large extent.

*Head of Institute, INDENTE–Institute of Innovative Oral Surgery and Medicine, Centre for Tissue Engineering, Hanover, Germany.

†Member of Institute, INDENTE–Institute of Innovative Oral Surgery and Medicine, Centre for Tissue Engineering, Hanover, Germany.

Reprint requests and correspondence to:

Karl-Heinz Schuckert, DMD, MD, PhD; Institute of Innovative Oral Surgery and Medicine; Centre for Tissue Engineering; Ellernstraße 23; D-30175 Hanover, Germany; Phone: (49) 511-8506232; Fax: (49) 511-281757; E-mail: info@indente.de

© 2006 Lippincott Williams & Wilkins, Inc.