Articles: PDF OnlyIngram Marylou; Shelden, Hunter C.; Jacques, Skip; Skillen, Ralph G.; Bradley, William G.; Techy, Geza B.; Freshwater, Donald B.; Abts, Richard M.; Rand, Robert W.Journal of Biological Response Modifiers: October 1987 Buy Abstract Summary: An immunotherapy protocol based on intracranial implantation of stimulated, autologous lymphocytes into the tumor bed following surgical debulking of malignant glioma is described. Phase I clinical trials in human patients are now in progress. Preliminary data representing the first 39 patients treated are presented briefly. Received October 8, 1986; accepted February 13, 1987. Address correspondence and reprint requests to Dr. M. Ingram at Experimental and Clinical Immunotherapy Laboratory, Huntington Medical Research Institutes, 99 North El Molino Avenue, Pasadena, CA 91101, U.S.A. © Lippincott-Raven Publishers.