Short Communication: PDF OnlyVugrin Davor; Hood, Linda; Laszlo, JohnJournal of Biological Response Modifiers: August 1986 - p 309-312 Buy Abstract Summary Seventeen patients with metastatic renal cancer were treated with human lymphoblastoid cell-derived alpha interferon, 30 × 106 U/m2, which was given intravenously for 3 consecutive days of each week for 6 weeks. On the days of interferon treatment only, patients received prednisone, 15 mg t.i.d., in order to minimize toxicity. Of the 16 evaluable patients, one had a minor regression of disease, eight had stable metastatic disease, and seven progressed. Constitutional symptoms, such as fever, anorexia, and fatigue, were common. Debilitating degrees of malaise were a treatment-limiting factor. © Lippincott-Raven Publishers.