Anterior segment optical coherence tomography to differentiate adenoviral subepithelial infiltrates and scars
Subepithelial corneal infiltrates often follow adenoviral keratoconjunctivitis. They usually resolve over time, but in some, these can progress to permanent corneal scars. Anterior segment- optical coherence tomography (S-OCT) can be a very useful tool to differentiate reversible infiltrates from irreversible scars and obviates the need for a steroid trial.
Subepithelial corneal infiltrates [Fig. 1a] appear on AS-OCT patchy, anterior stromal hyperreflective lesions with an intact Bowman's membrane and a uniform epithelial thickness [Fig. 1b]. On the other hand, scars [Fig. 1c] on AS-OCT appear as hyperreflective plaque-like lesions in the anterior stroma with disruption of the Bowman's membrane and variable epithelial thickness due to epithelial remodeling [Fig. 1d].
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© 2019 Indian Journal of Ophthalmology | Published by Wolters Kluwer – Medknow
1. Dawson CR, Hanna L, Wood TR, Despain R. Adenovirus type 8 keratoconjunctivitis in the United States. 3. Epidemiologic, clinical, and microbiologic features Am J Ophthalmol. 1970;69:473–80