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Gök, Mustafa; Karabaş, V Levent1; Emre, Ender2; Akşar, Arzu T3; Aslan, Mehmet Ş4; Ural, Dilek2

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Indian Journal of Ophthalmology: August 2015 - Volume 63 - Issue 8 - p 688
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We would like to thank the authors for their valuable contributions and criticism.

There are many factors known to affect the choroidal thickness. Age, axial length, and spherical equivalent are the most emphasized reasons that affecting choroidal thickness.[1234]

We also considered these and other factors to demonstrate essential hypertension isolated effect on choroidal thickness. Therefore, to exclude the effects of axial length and spherical equivalent on choroidal thickness only the participants had a refractive error in the range + 3.0 to − 3.0 diopters included in the study. Hence, there were any statistically significant difference between the each patient, control and patient subgroups regarding axial length and spherical equivalent.

Bilateral vertical and horizontal single line subfoveal choroidal thickness (SFCT) were considered to measure an average SFCT thickness. Manjunath et al. and Margolis and Spaide[15] determined the greatest choroidal thickness at the subfoveal area and decreased regularly both nasal and temporal directions. Hence, the choroidal layer did not show an irregular topographic variation in the light of these studies. The average values of axial length and spherical equivalent in these studies were similar to our study and also we have detected a similar topographic view in our study.

The only SFCT has been evaluated to reveal an association with a number of factors in the Beijing Eye Study (the largest-scale study on choroidal thickness) and subsequent works.[26] We only evaluated SFCT to avoid a statistical data confusion because of the presence of many other parameters associated with essential hypertension.

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Conflicts of interest

There are no conflicts of interest.

1. Margolis R, Spaide RF. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes Am J Ophthalmol. 2009;147:811–5
2. Wei WB, Xu L, Jonas JB, Shao L, Du KF, Wang S, et al Subfoveal choroidal thickness: The Beijing eye study Ophthalmology. 2013;120:175–80
3. Fujiwara T, Imamura Y, Margolis R, Slakter JS, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes Am J Ophthalmol. 2009;148:445–50
4. Flores-Moreno I, Lugo F, Duker JS, Ruiz-Moreno JM. The relationship between axial length and choroidal thickness in eyes with high myopia Am J Ophthalmol. 2013;155:314–319.e1
5. Manjunath V, Taha M, Fujimoto JG, Duker JS. Choroidal thickness in normal eyes measured using cirrus HD optical coherence tomography Am J Ophthalmol. 2010;150:325–329.e1
6. Xu J, Xu L, Du KF, Shao L, Chen CX, Zhou JQ, et al Subfoveal choroidal thickness in diabetes and diabetic retinopathy Ophthalmology. 2013;120:2023–8
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