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Abdominal Radical Trachelectomy for Early-Stage Cervical Cancer During Pregnancy

A Provocative Surgical Approach. Overview of the Literature and a Single-Institute Experience

Rodolakis, Alexandros, MD, PhD*; Thomakos, Nikolaos, MD, PhD*; Sotiropoulou, Maria, MD, PhD; Kypriotis, Konstantinos, MD*; Valsamidis, Dimitrios, MD, PhD; Bourgioti, Charis, MD§; Moulopoulou, Lia Evangelia, MD, PhD§; Vlachos, Georgios, MD, PhD*; Loutradis, Dimitrios, MD, PhD*

International Journal of Gynecological Cancer: November 2018 - Volume 28 - Issue 9 - p 1743–1750
doi: 10.1097/IGC.0000000000001357
Cervical Cancer

Objective Treatment of pregnancy complication due to malignancy of the cervix constitutes a great clinical challenge between optimal maternal therapy and fetal viability. Radical trachelectomy in early-stage cervical cancer during pregnancy instead of radical hysterectomy presents an alternative approach that can offer a satisfactory outcome for the mother and fetus.

Materials and Methods–Results A literature search of articles in English has been performed. Until now, 28 women with cervical cancer, including 2 who were managed and treated in our institute, who underwent a radical trachelectomy during pregnancy have been reported. We overviewed a total of 13 abdominal trachelectomies, 13 vaginal trachelectomies, and 2 laparoscopic trachelectomies.

Conclusions Radical trachelectomy can widen the therapeutic approach of early-stage cervical cancer in pregnant women who wish to preserve their pregnancy, providing a possibility of receiving the proper treatment with no delay.

*1st Obstetric and Gynaecological Department of “Alexandra” Hospital of National and Kapodistrian University of Athens;

Departments of Histopathology and

Anesthesiology, “Alexandra” General Hospital; and

§Department of Radiology “Aretaieion” Hospital of National and Kapodistrian University of Athens, Athens, Greece.

Address correspondence and reprint requests to Konstantinos Kypriotis, MD, 1st Obstetric and Gynaecological Department “Alexandra” Hospital of National and Kapodistrian University of Athens, Konstantinoupoleos 36, Nea Penteli, Athens, Greece 15236. E-mail:

Received January 23, 2018

Accepted July 30, 2018

© 2018 by the International Gynecologic Cancer Society and the European Society of Gynaecological Oncology.