We describe an exciting and novel surgical option, which may be used to treat formerly unresectable masses. This process is commonly referred to as autotransplantation (AuTn), and it combines the advances in transplant medicine and applies them to surgical oncology. The idea behind AuTn is the removal of the cancerous organ(s) to allow complete anatomic resection of the tumor mass, with consequent anastomotic reimplantation or AuTn of the now macroscopically tumor-free organ back into the patient. Autotransplantation has been used to remove large fibromatosis and desmoid tumors as well as malignant tumors. Our belief is that using lessons learned from the field of transplantation, AuTn can be applied in gynecologic oncology.
*Division of Surgery and Cancer, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital Campus, London, UK; †Division of Gynaecologic Oncology, Indiana University School of Medicine, Indianapolis, IN; ‡The Lister Hospital, Chelsea, London, UK; §West London Gynaecological Cancer Centre, Queen Charlotte’s Hospital, Hammersmith Hospital Campus, Imperial College, London, UK; ∥Small Bowel and Multivisceral Transplantation, Indiana University School of Medicine; and ¶Indiana University School of Medicine, Indianapolis, IN.
Address correspondence and reprint requests to Srdjan Saso, MBBS, BSc (Hons), MRCS, Division of Surgery and Cancer, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN. E-mail: firstname.lastname@example.org.
The authors declare no conflicts of interest.
Received November 27, 2012
Accepted December 23, 2012