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Effect of exercise on metabolic syndrome parameters in menopause women: a meta-analysis

Asiandi A.; Yen, M. F.; Wang, S. T.; Hsu, C. Y.
International Journal of Evidence-Based Healthcare: September 2014
doi: 10.1097/01.XEB.0000455120.52004.d5
Abstracts of Oral Presentations: Evidence Synthesis: PDF Only


It is essential to choose the best intervention in dealing with some parameters related with Metabolic Syndrome (MetS) or some diseases related with MetS including obesity, diabetes mellitus, and cardiovascular disease.


This study aim to assess the effect of exercise on MetS parameters in menopausal women.


This is a meta-analysis by following the PRISMA Statement as a guideline. We searched articles from PubMed, Medline (Ovid), ScienceDirect Online, and The Cochrane Library (CENTRAL) published between 2000 to 2014. The quality of study was assessed using Jadad scale.


Four randomized controlled trials (RCTs) articles were included in meta-analysis of the total 1210 articles from the four databases. Exercise was indicated to have no significant effect on anthropometric parameters (body weight, BMI, WC, HpC, and WHp ratio) with SMD = −0.08 (95% CI: −0.18, 0.01; p = 0.09). Exercise also had no significant effect for the following parameters: blood pressure SMD = 0.08 (95% CI: −0.04, 0.20; p = 0.23); total cholesterol SMD = 0.06 (95% CI: −0.11, 0.23; p = 0.54); HDL cholesterol SMD = 0.01 (95% CI: −0.16, 0.18; p = 0.97); LDL cholesterol SMD = −0.01 (95% CI: −0.18, 0.16; p = 0.42); triglycerides SMD = 0.01 (95% CI: −0.16, 0.18; p = 0.29); 2-h glucose SMD = −0.37 (95% CI: −0.75, 0.00; p = 0.05); fasting insulin SMD = −0.16 (95% CI: −0.42, 0.11; p = 0.98); and 2-h insulin SMD = −0.24 (95% CI: −0.62, 0.13; p = 0.20). Exercise had a significant effect on fasting glucose SMD = −0.35 (95% CI: −0.52, −0.18; p < 0.0001).


The results showed that exercise has no significant effect on anthropometric parameters, blood pressure, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, 2-h glucose, fasting insulin, and 2-h insulin. However, exercise has a significant effect on fasting glucose in menopausal women.


Exercise can effectively reduced blood glucose in menopause women.

International Journal of Evidence-Based Healthcare © 2014 The Joanna Briggs Institute

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