Considering the importance of family caregivers in pressure injury prevention, it is necessary to clearly define their role in pressure injury prevention guidelines. We reviewed the contents of pressure injury prevention guidelines with the aim of defining the role of family caregivers. PubMed, Web of Science, Scopus, and Proquest were searched, as well as the internet, as some pressure injury guidelines may not be published in professional journals. Literature published between 2000 and 2020 was searched using the keywords “pressure injury,” “pressure ulcer,” “bed sore,” and “prevention guideline.” Ten guidelines related to pressure injury prevention were found. Of these, five guidelines mentioned the role of family caregivers in relation to pressure injury, referring only to the training and empowerment of family caregivers. Of the five guidelines that mentioned caregiver training, only three determined the training content in detail. According to these guidelines, family caregivers should be trained on the risk factors of pressure injuries, characteristics of pressure injuries, intervention to prevent pressure injuries, nutrition, sign and symptoms of pressure injuries, complication such as infection and using protective equipment and devices. In the guidelines that focused on family caregivers, the attention is sometimes limited and vague. Limited attention to the role of family caregivers can lead to lack of awareness and reduced ability of family caregivers to prevent pressure injury and ultimately increase the patient's risk of developing pressure injury.