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Rapid Analysis of 239,238Pu, 241Am, and 90Sr for Nasal Smear Samples in Radiation Emergency and Evaluation of Intake Retention Fraction

Yoon, Seokwon; Ha, Wi-Ho; Park, Sunhoo; Lee, Seung-Sook; Jin, Young-Woo

doi: 10.1097/HP.0000000000000635

The efficiency of the nasal smear method was reviewed to perform a method of sample collection, analysis and initial dose estimation. The screening method of alpha-emitting radionuclides using chemical separation and alpha spectrometry was also studied. To rapidly conduct the appropriate response to victims, special monitoring for 239,238Pu, 241Am, and 90Sr using sequential analysis was established, and the method was successfully validated through participation in an international inter-comparison program. The duration of the analysis method was evaluated with regard to application in emergency situations because of its relatively rapid treatment and counting time. The intake retention fraction was calculated and evaluated to review the characteristics of each radionuclide in the anterior nasal passage of the extra-thoracic region. No large difference was observed among the four radionuclides. However, the values of the intake retention fraction were affected by age groups because of the different respiratory rates. The effects of the 90Y ingrowth and particle size were also discussed.

*Korea Institute of Radiological and Medical Sciences, Seoul, Korea.

This study was supported by a grant of the Korea Institute of Radiological and Medical Sciences (KIRAMS), funded by Ministry of Science, ICT and Future Planning, Republic of Korea. (1711031808/50581‐2016).

For correspondence contact: Wi-Ho Ha, National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul, Korea, or email at

(Manuscript accepted 27 October 2016)

© 2017 by the Health Physics Society