ArticleTraumatic Brain Injury Research Since the 1998 NIH Consensus Conference Accomplishments and Unmet GoalsRagnarsson, Kristjan T. MDAuthor Information Department of Rehabilitation Medicine, Mount Sinai School of Medicine, New York, NY. Corresponding author: Kristjan T. Ragnarsson, MD, Department of Rehabilitation Medicine, Mount Sinai School of Medicine, 1425 Madison Ave, Box 1240, New York, NY 10029 (e-mail: [email protected]). Presented at the Second Federal Interagency Conference on Traumatic Brain Injury: Integrating Models of Research and Service Delivery, Bethesda, Md, March 10, 2006. The preparation of this manuscript was supported in part by the National Institute on Disability and Rehabilitation Research, US Department of Education (grant H133A021918). Journal of Head Trauma Rehabilitation: September 2006 - Volume 21 - Issue 5 - p 379-387 Buy Abstract In 1998, an NIH sponsored Consensus Conference on Traumatic Brain Injury (TBI) Rehabilitation identified 30 different areas of needed research. A comprehensive review of recently generated research knowledge in the field of TBI has shown that a large number of Class III and IV evidence studies have been published, but relatively few of the more scientifically rigorous Class I or II studies. A rapid growth of publications on TBI rehabilitation has generated new knowledge in the epidemiology of TBI, the management of TBI and its secondary medical complications, rehabilitation of cognitive impairment, impact of TBI on community integration and quality of life, incidence of psychiatric dysfunction, and how caregivers and family members are affected. However, there is need to replicate many of these studies using more scientifically rigorous methodologies, while other areas of important TBI research remain largely unexplored. © 2006 Lippincott Williams & Wilkins, Inc.