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Saturday, March 1, 2014

Trailers (75): Gestational diabetes and sleep-disordered breathing

Bisson et al. Gestational diabetes mellitus and sleep-disordered breathing

Why should you read about this topic?

Everyone knows about sleep disturbances after delivery, but what about during pregnancy?

What were the authors trying to do?

Determine if gestational diabetes (GDM) is associated with sleep-disordered breathing

Who participated and in what setting?

Pregnant women with (N=26) or without (N=26) GDM at 24-32 weeks gestation and a BMI<35 kg/m2 followed at university-based clinics in Quebec during 2010-2 underwent polysomnography at home.

What was the study design?

Cross-sectional case-control

What were the main outcome measures?

Apnea-hypopnea index (events per hour)

What were the results?

The apnea-hypopnea index was not different between groups.  Although women with GDM had more sleepiness, other measures of sleep disturbance were not different between groups.

What is the most interesting image in the paper?

Table 2

What were the study strengths and weaknesses?

Strengths: careful evaluation of sleep-disordered breathing; subjects matched for BMI. Weaknesses: underpowered for significant sleep disorders; women with a BMI>35 not studied

What does the study contribute for your practice?

GDM is not associated with sleep-disordered breathing when the woman’s pre-pregnancy BMI is <35 kg/m2