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ACOG Publications

ACOG Committee Opinion No. 771 Summary: Umbilical Cord Blood Banking

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doi: 10.1097/AOG.0000000000003129
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Abstract

Recommendations

The American College of Obstetricians and Gynecologists makes the following recommendations regarding umbilical cord blood banking:

  • Umbilical cord blood collected from a neonate cannot be used to treat a genetic disease or malignancy in that same individual (autologous transplant) because stored cord blood contains the same genetic variant or premalignant cells that led to the condition being treated.
  • The routine collection and storage of umbilical cord blood with a private cord blood bank is not supported by the available evidence.
  • The current indications for umbilical cord blood transplantation are limited to select genetic, hematologic, and malignant disorders.
  • Private umbilical cord blood banking may be considered when there is knowledge of a family member with a medical condition (malignant or genetic) who could potentially benefit from cord blood transplantation.
  • Public umbilical cord blood banking is the recommended method of obtaining umbilical cord blood for use in transplantation, immune therapies, or other medically validated indications.
  • Families of all ethnicities and races should consider the societal benefit of public umbilical cord blood donation to increase the availability of matched cord blood units for people of all backgrounds.
  • Obstetrician–gynecologists and other obstetric care providers should be aware of state and local laws regarding umbilical cord blood banking, including the law in some states that requires physicians to inform patients about umbilical cord blood banking options.
  • Health care providers with a financial interest in private umbilical cord blood banking should disclose these interests, incentives, or other potential conflicts of interest.
  • If a patient requests information about umbilical cord blood banking, balanced and accurate information regarding the advantages and disadvantages of public and private umbilical cord blood banking should be provided.
  • A variety of circumstances may arise during the process of labor and delivery that may preclude adequate collection.
  • Umbilical cord blood collection should not compromise obstetric or neonatal care or alter routine practice of delayed umbilical cord clamping with the rare exception of medical indications for directed donation.
  • It is important to inform patients that the medical condition of the woman or neonate may prevent adequate umbilical cord blood collection.

© 2019 by the American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.