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A Pregnant Patient With Ebola Virus Disease

Oduyebo, Titilope, MD, MPH; Pineda, Denis, DrMed, MPH; Lamin, Manjo, CHO, DCMH; Leung, Anders, BSc; Corbett, Cindi, PhD; Jamieson, Denise J., MD, MPH

doi: 10.1097/AOG.0000000000001092
Contents: Case Report
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Video Abstract

BACKGROUND: Limited data suggest Ebola virus disease during pregnancy is associated with high maternal and fetal mortality.

CASE: A 34-year-old woman, gravida 4 para 3, at 36 weeks of gestation was admitted to an Ebola treatment unit in Sierra Leone with Ebola virus disease confirmed by laboratory testing of maternal blood for Ebola RNA. She complained of headache, cough, and arthralgia for 7 days but was afebrile. Eleven days later, intrauterine fetal death was diagnosed; the following day, maternal blood was negative for Ebola viral RNA. Labor was induced and resulted in the vaginal delivery of a stillborn fetus. The mother recovered. Her vaginal secretions (on the day of induction), a placenta fragment, umbilical cord, and neonatal buccal swabs were positive for Ebola RNA. No exposed health care workers were infected.

CONCLUSION: This case illustrates that pregnant women can survive infection with Ebola virus disease and be cared for and delivered without infection of their health care workers.

Pregnant women can survive Ebola virus disease; with infection prevention and control practices, health care providers can deliver obstetric care safely.

Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia; Médecins Sans Frontières–Operational Centre Brussels, Kailahun, Sierra Leone; Kailahun District Health Management Team, Department of Surveillance, Sierra Leone Ministry of Health and Sanitation; the Health Department of Bremen, Bremen, Germany; and the National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

Corresponding author: Titilope Oduyebo, MD, MPH, CPH, Epidemic Intelligence Service Officer, Division of Reproductive Health, Center for Chronic Disease Prevention and Health Promotion; e-mail: ydk7@cdc.gov.

We thank Livia Tampellini and Ruth Kauffman and all the Médecins Sans Frontières and local staff for their expertise and support in taking care of this patient.

The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

For a Video Abstract of this article, visit http://links.lww.com/AOG/A690.

Financial Disclosure The authors did not report any potential conflicts of interest.

© 2015 by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.