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Acute Respiratory Distress Syndrome After Uterine Artery Embolization

Nguyen, Dong Bach, MD; How, Jeffrey, MD, MPH; Ziegler, Cleve, MD; Madar, Jaclyn, MD

doi: 10.1097/AOG.0000000000002875
Leiomyomas: Case Report: PDF Only

INTRODUCTION: Although uterine artery embolization has been established as a less invasive alternative to hysterectomy or myomectomy for the treatment of uterine leiomyomas, it is not devoid of life-threatening complications.

CASE: We present the case of a 44-year-old patient who developed a severe systemic inflammatory response and acute respiratory distress syndrome 5 weeks after uterine artery embolization of a large multileiomyomatous uterus. Deterioration of her clinical status prompted an emergency hysterectomy that led to rapid improvement.

CONCLUSION: Although fatalities from septicemia after uterine artery embolization have been reported, aseptic inflammatory responses to uterine degeneration can also lead to multiorgan failure. With recent studies refuting uterine size and leiomyoma location as risk factors, further research is needed to help select appropriate uterine artery embolization candidates.

Systemic inflammatory response and acute respiratory distress syndrome are rare, life-threatening complications after uterine artery embolization for leiomyomas that may require emergency hysterectomy as treatment.

Department of Obstetrics & Gynecology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

Corresponding author: Dong Bach Nguyen, MD, Department of Obstetrics & Gynecology, McGill University, 3755 Chemin de la Cote-Ste-Catherine, Montreal, QC H2T 1E2, Canada; email: dong.bach.nguyen@mail.mcgill.ca.

Financial Disclosure The authors did not report any potential conflicts of interest.

Each author has indicated that he or she has met the journal's requirements for authorship.

Received May 14, 2018

Received in revised form July 05, 2018

Accepted July 12, 2018

© 2018 by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.