Embryonal rhabdomyosarcoma of the cervix is a rare and aggressive malignancy that usually affects children and young adults.
We describe a 2-year-old patient who presented with a mass protruding through the vaginal introitus. Preoperative investigations including vaginoscopy, hysteroscopy, magnetic resonance imaging, and biopsies confirmed embryonal rhabdomyosarcoma, botryoid subtype, arising from the cervix. She was successfully treated with neoadjuvant chemotherapy and interval laparoscopic radical trachelectomy to achieve remission.
Collaboration between the pediatric and adult surgical and medical oncology teams was critical to implement this fertility-sparing treatment strategy in such a young girl having this rare tumor.
Fertility-preserving radical trachelectomy preceded by neoadjuvant chemotherapy was a successful treatment strategy for a 2-year-old girl with embryonal rhabdomyosarcoma of the cervix.
Division of Gynecologic Oncology, Department of Surgery and Surgical Oncology, University Health Network, Princess Margaret Cancer Centre, the Department of Obstetrics and Gynecology, University of Toronto, and the Section of Pediatric Gynecology, Division of Endocrinology, the Division of Pediatric Urology, Department of Surgery, and the Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
Corresponding author: Taymaa May, MD, MSc, Princess Margaret Cancer Center, 610 University Avenue, OPG Wing 6-811, Toronto, ON M5G 2M9, Canada; email: firstname.lastname@example.org.
Financial Disclosure The authors did not report any potential conflicts of interest.
Each author has indicated that he or she has met the journal's requirements for authorship.
Peer review history is available at http://links.lww.com/AOG/B173.