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Abnormal Vaginal Bleeding in Women Desiring Contraception Who Are Taking Anticoagulation Therapy

Bonnington, Adam, MD; Autry, Amy M., MD

doi: 10.1097/AOG.0000000000002518
Contents: Clinical Conundrums

A 30-year-old nulligravid woman is referred to you for heavy menstrual cycles. Although her menstrual cycles were previously light, she was recently diagnosed with an unprovoked lower extremity venous thromboembolism and is taking anticoagulation therapy after a negative thrombophilia workup. She wants help with her vaginal bleeding and desires contraception.

Because it suppresses ovulation, depot medroxyprogesterone is the preferred treatment choice for contraception and abnormal uterine bleeding in women taking anticoagulation therapy.

University of California, San Francisco, San Francisco, California.

Corresponding author: Amy M. Autry, MD, 2356 Sutter Street, J-140, San Francisco, CA 94115; email:

Financial Disclosure The authors did not report any potential conflicts of interest.

Each author has indicated that he or she has met the journal's requirements for authorship.

© 2018 by American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.