To compare the effect of selective fetal reduction procedure on obstetric outcome of triplets conceived after in vitro fertilization and embryo transfer.
This is a retrospective cohort study that included 64 triplet pregnancies that occurred in the period between 1/1/2007 to 12/31/2014 at our IVF unit. Patients were divided into 2 groups. Group 1 consisted of 15 patients who underwent a selective fetal reduction procedure, while group 2 included 49 patients who did not go for a fetal reduction procedure. The primary outcomes were: gestational age at delivery and average birth weight.
There were no significant differences in underlying etiology of infertility, maternal BMI (26.1±6.3 vs 26.0±7.3 kg/m2), gestational age at birth (30.7±9.6 vs 32.1±5.9 weeks), incidence of preterm birth rate (83.3% vs 75.6%) and live birth rate after viability (80.0% vs 91.8%) between group 1 and 2 respectively. However, there were significant differences in maternal age (35.7±3.7 vs 32.6±3.9 years P<.01) and average birth weight (2671.3±887.4 vs 1813.9±631.4 grams P<.01) between group 1 and 2, respectively.
Our data suggests that selective fetal reduction procedures can improve triplet pregnancy outcome by increase the average birth weight by 857.4 grams or 47%. Further studies with larger sample size are needed to guide patient counseling and decision regarding selective fetal reduction in triplet pregnancies.