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Average-Risk Pregnant Patient Perspectives on Noninvasive Prenatal Testing

Shields Andrea D. MD; Vidosh, Jacqueline D. MD
Obstetrics & Gynecology: May 2014
doi: 10.1097/01.AOG.0000447402.08928.5f
Monday, April 28, 2014: PDF Only

INTRODUCTION: The objective of this study was to evaluate average-risk pregnant patients' perspectives on use of noninvasive prenatal testing.

METHODS: A 31-question survey was distributed to patients attending group prenatal genetic counseling taught by a single maternal-fetal medicine specialist between 6 and 8 weeks of gestation. The survey queried average-risk pregnant patient perspectives on the potential use of noninvasive prenatal testing in pregnancy.

RESULTS: This institutional review board-approved survey was distributed to 95 patients attending the counseling between March and July 2013. A total of 84 average-risk patients were included in this analysis. The majority of patients reported that they would elect to perform noninvasive prenatal testing over amniocentesis or no testing for any fetal abnormality on ultrasonography. A majority of patients reported they favored noninvasive prenatal testing over invasive testing if they had an abnormal serum screen result (67.9%). One third of the patients would undergo invasive testing if the noninvasive prenatal testing results were abnormal with over 50% of patients in this group indicating that the results might affect their decision to continue the pregnancy. A total of 28.6% of patients would elect invasive testing if the noninvasive prenatal testing results were inconclusive. If noninvasive prenatal testing results were normal but subsequent ultrasound results revealed a major finding, 40.5% of participants would undergo an amniocentesis.

CONCLUSION: In our population, the majority of average-risk pregnant women report that noninvasive prenatal testing is preferred to invasive testing for abnormal serum screening or ultrasonography. One third of patients would elect for invasive testing if the noninvasive prenatal testing returned abnormal, which may affect their decision to continue the pregnancy.

Financial Disclosure: Andrea D. Shields, MD, and Jacqueline D. Vidosh, MD—These authors have no conflicts of interest to disclose relative to the contents of this presentation.

© 2014 by The American College of Obstetricians and Gynecologists.