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Solitary Fibrous Tumors Arising From the Female Pelvis

Sueblinvong, Thanasak MD; Judson, Patricia L. MD; Downs, Levi S. Jr MD; Argenta, Peter A. MD

doi: 10.1097/AOG.0b013e31821b2037
Case Reports
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BACKGROUND: Solitary fibrous tumor is a rare mesenchymal tumor reported initially in the pleura but that is now reported in widely ranging anatomic sites with a variable clinical course. Solitary fibrous tumor arising from the female genital tract is extremely rare and the management of this condition is controversial.

CASES: We report three cases of female genital tract solitary fibrous tumors displaying different clinical behaviors and review literature with regard to diagnosis, possible prognostic factors, and management of this tumor.

CONCLUSION: The primary treatment of this disease should be surgical. The rarity and disparate clinical manifestations of this disease preclude a definitive statement on use and optimization of adjuvant therapy. Nevertheless, both pathologic and clinical findings may be useful in gauging risk and assessing the merits of individualized adjuvant therapy.

The primary treatment of pelvic solitary fibrous tumors is surgical, with adjuvant therapy dictated by both clinical and pathologic findings.

From the Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology University of Minnesota, Minneapolis, Minnesota.

Corresponding author: Peter A. Argenta, MD, MMC, 395 420 Delaware Street SE, Minneapolis, MN 55455; e-mail: argenta@umn.edu.

Financial Disclosure The authors did not report any potential conflicts of interest.

© 2011 The American College of Obstetricians and Gynecologists