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Giant Cell Bone Tumor of the Thoracic Spine Presenting in Late Pregnancy

Kathiresan, Anupama S. Q. MD; Johnson, Jeremiah N. MD; Hood, Brian J. MD; Montoya, Simone P.; Vanni, Steven DO; Gonzalez-Quintero, Victor H. MD, MPH

doi: 10.1097/AOG.0b013e31821081a2
Case Reports

BACKGROUND: We report a case of a large giant cell tumor of the thoracic spine presenting with spinal cord compression during pregnancy.

CASE: A 24-year-old woman presented at term with lower back pain, bilateral lower extremity weakness, numbness, and bowel and bladder incontinence. Magnetic resonance imaging revealed a spinal soft tissue mass compressing the spinal cord. The patient delivered a healthy girl by cesarean then underwent a T8-T9 laminectomy, posterior spinal decompression, and instrument fusion. Two days later, she had a thoracotomy, corpectomy of the vertebral body, and anterior tumor debulking. Ultimately, the patient was discharged to inpatient rehabilitation with improved lower extremity strength and returned bowel and bladder function.

CONCLUSION: Obstetricians should be vigilant regarding progressive neurologic symptoms during pregnancy.

This is an unusual case of acute spinal cord compression during pregnancy secondary to giant cell tumor of the thoracic spine.

From the Department of Obstetrics and Gynecology and the Department of Neurosurgery, University of Miami, Miller School of Medicine, Miami, Florida.

Corresponding author: Anupama S. Q. Kathiresan, MD, 1611 NW 12th Avenue, Holtz Building Suite 4070, Department of Obstetrics and Gynecology, Miller School of Medicine, University of Miami/Jackson Memorial Hospital, Miami, FL 33136; e-mail:

Financial Disclosure The authors did not report any potential conflicts of interest.

© 2011 The American College of Obstetricians and Gynecologists