Malignant transformation of endometriosis in an episiotomy site is rare.
A 42-year-old woman presented with a palpable mass, 2.5 cm in size, just inside the posterior commissure of the vagina, at the site of a previous episiotomy for a vaginal delivery. Three years previously, an endometriotic cyst had been excised at the same site, and the patient had been treated with a gonadotropin-releasing hormone analogue for 6 months. Biopsy revealed a clear cell adenocarcinoma arising in endometriosis. The patient underwent radical surgery alone without adjuvant therapy. At 10-month follow-up, there was no evidence of recurrence.
Patients who experience a recurrence of extragonadal endometriosis after prior therapy should be monitored carefully for malignant degeneration.
A clear cell carcinoma arose in endometriosis of a previous episiotomy site.
From the 1Department of Obstetrics and Gynecology and the 2Department of Pathology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea.
Corresponding author: Joo-Hyun Nam, 138-736 Pungnap-2-dong 388-1 Songpa-gu, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea; e-mail: firstname.lastname@example.org.
Financial Disclosure The authors have no potential conflicts of interest to disclose.