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Pandemic Influenza and Pregnancy: A Call for Preparedness Planning

Beigi, Richard H. MD, MSc1

doi: 10.1097/
Current Commentary

With the emerging infectious disease threat of pandemic avian influenza, obstetricians should be aware of the disproportionate morbidity and mortality documented among gravidas in the twentieth century pandemics. To date the majority of fatal cases of H5N1 avian influenza have been recorded in young previously healthy adults, reminiscent of the epidemiology of the 1918 “Spanish flu” pandemic. All providers of obstetric services and all facilities providing obstetric care have a key role in terms of pandemic planning for our potentially disproportionately affected, vulnerable patient population. This article summarizes the relevant data and frames the current threat to obstetric providers and facilities posed by H5N1 avian influenza in terms of pandemic potential. In addition, suggestions for basic pandemic planning efforts are reviewed.

Pregnant women have experienced disproportionate morbidity and mortality in past influenza pandemics, making planning efforts critical to the optimal care of our patient population.

From the 1Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Corresponding author: Richard H. Beigi, MD, MSc, Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Reproductive Infectious Diseases, Magee-Womens Hospital, University of Pittsburgh Medical Center, 300 Halket Street, Pittsburgh, PA 15213; e-mail:

© 2007 by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.