A regimen including interferon-α has become the standard of care in the treatment of chronic hepatitis C over the last decade. One rare adverse effect associated with the use of interferon-α is a granulomatous pulmonary reaction.
A unique case of uterine sarcoidosis associated with the use of interferon-α for chronic hepatitis C infection is presented.
Gynecologists should be aware of a potential association between interferon-α therapy and granulomatous reactions occurring not only in the lung but also in the female genital tract.
Uterine granulomatous reactions are a potential adverse effect of interferon-α therapy for chronic hepatitis C infection.
*Henry Dunant Hospital, Athens; and †Athens University Medical School, Athens, Greece
Received March 31, 2004. Received in revised form May 7, 2004. Accepted June 9, 2004.
Address reprint requests to: Sotirios Tsiodras, md, dsci, 4th Department of Internal Medicine, University of Athens Medical School, 24 Agias Barbaras Street, 14451 Athens, Greece; e-mail: firstname.lastname@example.org.