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Hochfeld Marla MD; Druzin, Maurice L. MD; Maia, Diane MD; Wright, Jennifer BS; Lambert, Elaine R. MD; McGuire, James MD
Obstetrics & Gynecology: May 1994
Pregnancy complicated by primary antiphospholipid antibody syndrome: PDF Only

Background: Primary antiphospholipid antibody syndrome is a clinical entity that may threaten the health of both fetus and mother.

Case: We report a fatal case of primary antiphospholipid antibody syndrome in a woman who developed catastrophic disease due to multisystem thrombosis in the postpartum period following a fetal death. Three years before her admission, primary antiphospholipid antibody syndrome was diagnosed on the basis of high titers of immunoglobulin G anticardiolipin antibody, a positive lupus anticoagulant, a false-positive VDRL, and fibrin deposits in the biopsy of a palmar lesion.

Conclusion: The physician must recognize the potentially catastrophic complications of pregnancy and the postpartum period in patients with antiphospholipid antibodies, and appropriate patient counseling should be provided.(Obstet Gynecol 1994;83:804-5)

© 1994 The American College of Obstetricians and Gynecologists