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Guy Glenford P. MD; Baxi, Laxmi V. MD; Hurlet-Jensen, Anne MD; Chao, Conrad R. MD
Obstetrics & Gynecology: September 1992
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Factor IX deficiency (hemophilia B, Christmas disease) is an X-linked recessive coagulation disorder. It occurs in one out of every 25,000–30,000 male births and requires even rarer genetic circumstances for phenotypic expression in females. We report the occurrence of a large, late-trimester subchorionic hematoma in a gravida with factor IX deficiency and with laboratory evidence of consumptive coagulopathy during treatment. The patient was managed conservatively and had a successful outcome at term. The only four reported cases of antepartum management of factor IX deficiency in the English literature are reviewed.

© 1992 The American College of Obstetricians and Gynecologists