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BADAWY SHAWKY Z. A. MD; NUSBAUM, MURRAY L. MD; OMAR, MOHAMMED MD
Obstetrics & Gynecology: January 1980
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Twenty-two women with galactorrhea and/or amenorrhea were evaluated. Thyroxine (T4), thyroid-stimulating hormone (TSH), and visual fields were normal. Hyperprolactinemia (22 to 440 ng/ml) was present in 19 patients. Evidence of tumor was found in 73.7% of the women, whereas 26.3% were classified as functional. Three patients with empty sella syndrome showed normal prolactin levels (12.2 to 18.5 ng/ml). There was a significant negative correlation between prolactin levels and follicle-stimulating hormone (FSH) (P<0.05), but not between prolactin and luteinizing hormone (LH) levels. Hypocycloidal polytomography was better than plain x-ray films in detecting early prolactin-secreting pituitary tumors (14 patients). Pituitary testing using an insulin tolerance test showed a statistically significant difference in human growth hormone (hGH) reserve between tumor and functional groups

© 1980 The American College of Obstetricians and Gynecologists