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INCREASED ALPHA FETOPROTEIN IN AMNIOTIC FLUID ASSOCIATED WITH A CONGENITAL ESOPHAGEAL ATRESIA OF THE FETUS

Seppälä, Markku, MD

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Elevated levels of alpha fetoprotein (AFP), a major plasma protein synthesized by the human fetus, in maternal serum and in amniotic fluid have been suggested as an antenatal indication of developmental disorders of the fetus. A case is reported of elevated levels of AFP in the amniotic fluid associated with fetal esophageal atresia.

From Department II of Obstetrics and Gynecology at University Central Hospital, Helsinki, Finland.

Supported by a Sigrid Juselius Foundation Grant.

Submitted for publication April 20, 1973.

The illustration at the top of the page, Avicenna, Galenus, Hippocrates, is from an early medical book. Wood cut, 1511 (The Bettmann Archive)

© 1973 by The American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.