The reproductive performances of 145 patients with molar pregnancy were reviewed. A total of 118 pregnancies occurred in 82 patients. Of the 63 patients who did not conceive, only 8 were attempting to become pregnant, an infertility rate of 8.9%. No increased incidence was noted in prematurity, congenital malformation, perinatal mortality or neonatal morbidity. Our data did indicate, however, that a higher rale of miscarriage occurred in patients treated with chemotherapy. This may reflect damage to the reproductive tract rather than any drug effect. One patient experienced three successive hydatidiform moles. This phenomenon is thought to be due to a unique but as yet undiagnosed predisposition rather than to chance occurrence.
© 1973 The American College of Obstetricians and Gynecologists