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ZÁRATE ARTURO MD; CANALES, ELIÁS S. MD; DE LA CRUZ, ANTONIO MD; SORIA, JORGE MD; SCHALLY, ANDREW V. PhD
Obstetrics & Gynecology: June 1973
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The pituitary resjmnse to the intravenous administration of 50 jig of synthetic LH-RH was studied in 6 patients with Stein-Lcventhal syndrome and 12 with functional amenorrhea. The results were compared with those obtained from 10 normal menstruating women. LH-RH released comparable amounts of FSH and LH in patients with Slein-Leventhal syndrome and normal eumenorrheic women. Patients with functional amenorrhea showed greater LH baseline levels and greater LH release after LH-RH, however FSH release was not significantly different in the three groups of patients. It is concluded from this study that the LH resjHinse to LH.RH is different between patients with Slein-Leventhal syndrome and functional amenorrhea suggesting that such resjKinse is likely determined by the level of circulating sex steroids and the concentration of endo. genous LH-RH

© 1973 The American College of Obstetricians and Gynecologists