Various criteria have been used to diagnose anemias secondary to iron deficiency. These include mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), serum iron and bone marrow examination. Faults, however, have been found with each of these methods. Recently, depressed iron saturation of transferrin (Fe/TIBC) has been found to be a reliable method of diagnosing iron deficiency anemia in the nonpregnant individual. This paper, which presents data from 53 pregnant patients, shows that red cell morphology, MCV, MCHC and serum iron values are less reliable than the Fe/TIBC ratio in diagnosing the iron-deficient state. It appears that the Fe/TIBC value is a more reliable indicator of iron deficiency in the antenatal patient.
From the Department of Obstetrics and Gynecology of the University of California, San Francisco, San Francisco, Calif 94122.
© 1971 The American College of Obstetricians and Gynecologists