Original Article: PDF OnlyEffect of Selected Estrogens and Progestins on Human Chromosomes In VitroSTENCHEVER, MORTON A. MD, FACOG; JARVIS, JANE A. MT; KREGER, N KRISTINE BAAuthor Information From the Department of Reproductive Biology, Case Western Reserve University, School of Medicine, Cleveland, Ohio Obstetrics & Gynecology: August 1969 - Volume 34 - Issue 2 - p 249-251 Free Abstract Several of the estrogens and progestins constituting the widely used contraceptive pills were added individually in varied concentrations to cultures of lymphocytes grown from the blood of healthy women. When compared to control cultures and evaluated in blind fashion, the in-vitro studies uncovered no obvious chromosomal effects. © 1969 The American College of Obstetricians and Gynecologists
