Carcinoma In Situ of the Cervix Uteri

A Study of 409 Patients

Abstract

Routine cytologic screening of the cervix of all women in the hospital and cervical biopsy daring curettage for incomplete abortion were responsible for finding 85% of the 409 in-situ carcinomas. More than half of the group were treated successfully by means of modified radical hysterectomy, but 35% of the excised uteri showed residual in-situ cancer. Sixty untreated patients were observed closely for at least 2 years; only 2 of these women required treatment for invasive carcinoma, which was detected through follow-up cytologic studies and confirmed by cone biopsy.