To study the correlation between known visual field
defects and retinal nerve fiber layer (RNFL) thickness detected by optical coherence tomography
(OCT) in glaucomatous eyes.
Materials and Methods Visual field
parameters and OCT RNFL measurements of 28 eyes of 28 glaucoma
patients with various stages of glaucoma
were compared with 38 eyes of 38 normal age-matched controls. A perimetric nerve fiber bundle map
was built by dividing the visual field
area into 21 zones. Mean deviation and pattern standard deviation values within these 21 zones were compared with OCT RNFL thickness measurements in 12 sectors and the results were analyzed.
Average RNFL thickness was 62.90±16.56 μm in the glaucoma
group and 111.90±6.00 μm in the control group (P
<0.05). Pattern standard deviation and mean deviation visual field
zones and corresponding OCT RNFL thickness sectors were significantly correlated at specific sectors in the glaucoma
Analysis of RNFL thickness in eyes with focal glaucomatous visual field
defects showed good structural and functional correlation with OCT. OCT contributes to the identification of focal defects in the RNFL of glaucoma