Case ReportsVisualization of Changes of the Iris Configuration After Peripheral Laser Iridotomy in Primary Melanin Dispersion Syndrome Using Optical Coherence TomographyLaemmer, Robert MD; Mardin, Christian Y. MD; Juenemann, Anselm G. M. MDAuthor Information Department of Ophthalmology, University of Erlangen-Nuremberg, Schwabachanlage, Erlangen, Germany Reprints: Robert Laemmer, MD, Department of Ophthalmology, University of Erlangen-Nuremberg, Schwabachanlage 6, 91054 Erlangen, Germany (e-mail: Robert.Laemmer@uk-erlangen.de). Received for publication August 9, 2007; accepted January 14, 2008 Journal of Glaucoma: October-November 2008 - Volume 17 - Issue 7 - p 569-570 doi: 10.1097/IJG.0b013e318168f02c Buy Metrics Abstract Pigment or melanin dispersion syndrome is characterized by radial iris transillumination defects, retrocorneal Krukenberg spindle, and dense trabecular pigmentation. Reverse pupillary block has been presumed as one possible pathogenetic mechanism for backward bowing of the iris leading to iris-zonular rubbing and distribution of melanin granules in the anterior chamber. Laser iridotomy is recommended as a treatment to prevent further melanin dispersion and development of pigmentary glaucoma. The effect of Nd:YAG laser iridotomy as a prophylactic and potentially causal treatment in melanin dispersion syndrome can be easily visualized by optical coherence tomography as a fast and noncontact procedure. © 2008 Lippincott Williams & Wilkins, Inc.