Original StudiesChanges in Angle Configuration After Phacoemulsification Measured by Anterior Segment Optical Coherence TomographyNolan, Winifred P. MD, FRCOphth*; See, Jovina L. MBBChir, FRCS(Ed)†; Aung, Tin PhD, FRCS(Ed)† ‡; Friedman, David S. MD, MPH§; Chan, Yiong-Huak PhD∥; Smith, Scott D. MD, MPH¶; Zheng, Ce MSc, MD∥; Huang, David MD, PhD♯; Foster, Paul J. PhD, FRCS(Ed)** ††; Chew, Paul T. K. FRCS(Ed), FRCOphth† ∥ Author Information *Birmingham and Midland Eye Centre, Birmingham **Department of Epidemiology, Institute of Ophthalmology ††Glaucoma research unit, Moorfields Eye Hospital, London, UK †National University Hospital ‡Singapore National Eye Centre ∥National University of Singapore, Singapore §Wilmer Eye Institute and Johns Hopkins Bloomberg School of Public Health, Baltimore, MD ¶Cole Eye Institute, Cleveland, OH ♯Doheny Eye Institute, University of Southern California Keck School of Medicine, Los Angeles, CA Financial support: National University of Singapore: Grant nos. R-191000007101 and R-191000007112. Reprints: Dr Winifred P. Nolan, MD, FRCOphth, Birmingham and Midland Eye Centre, Dudley Road, Birmingham B18 7QU, UK (e-mail: [email protected]). Received for publication December 29, 2006; accepted December 7, 2007 Journal of Glaucoma 17(6):p 455-459, September 2008. | DOI: 10.1097/IJG.0b013e3181650f31 Buy Metrics Abstract Purpose To measure changes in angle width after phacoemulsification and intraocular lens (IOL) implantation using anterior segment optical coherence tomography (AS-OCT). Materials and Methods Twenty-one patients undergoing cataract surgery were recruited from the National University Hospital, Singapore. AS-OCT images were obtained of nasal and temporal angle quadrants before and at 1-month after surgery. Optical measurements of central anterior chamber depth were obtained, and gonioscopic measurement of angle width was recorded. AS-OCT angle width parameters measured in the nasal and temporal quadrants included the angle opening distance at 500 μm (AOD500) anterior to the scleral spur and the trabecular iris surface area at 750 μm (TISA750) anterior to the scleral spur. Preoperative and postoperative measurements were compared using paired samples t tests. Results Data were collected from 21 eyes of 21 subjects with cataract. Seven subjects also had gonioscopic evidence of primary angle closure. Mean anterior chamber depth increased from 2.92 (±0.54) to 4.24 (±0.57) mm (P=0.044) after cataract extraction. There was a significant increase in AS-OCT parameters for both nasal and temporal angles after surgery. An 88.2% increase in AOD500 was measured for the nasal angle quadrant with a mean difference of 213.9 (±173) μm (P<0.001). TISA750 increased by 94.4% in the nasal angle with a mean difference of 0.134 (±0.104) μm2 (P<0.001). Conclusions AS-OCT imaging demonstrates increases in angle width after cataract extraction. © 2008 Lippincott Williams & Wilkins, Inc.